Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Characterization of Novel <i>Lachancea thermotolerans</i> Strains for Application in Table Olive Fermentation. [PDF]
Gil-Flores P +2 more
europepmc +1 more source
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen +8 more
wiley +1 more source
Insights into Neuromuscular Function in Older Adults from Functional Data Analysis of Time-Dependent Handgrip Strength Curves. [PDF]
Urbano D, Inácio M, Restivo MT.
europepmc +1 more source
Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang +12 more
wiley +1 more source
Linking aerobic scope to fitness in the wild reveals potential opportunities to help recover imperiled salmon populations. [PDF]
Burford BP +8 more
europepmc +1 more source
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
Bioprospection of entomopathogenic fungi natives of Brazilian Semi-arid with potential for biological control of Insect-pests. [PDF]
Santos TS +6 more
europepmc +1 more source
Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee +9 more
wiley +1 more source
A comparison of vendor artificial intelligence solutions for automated post-processing of short-axis cine images in cardiovascular magnetic resonance imaging. [PDF]
Hadler T +8 more
europepmc +1 more source

