Results 81 to 90 of about 17,965 (234)

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Production Of The Nucleocapsid Protein Of A Swine Nipah Virus Isolate In Escherichia Coli [PDF]

, 2002
Nipah virus (NiV) possesses a nonsegmented, single-stranded negative sense RNA genome that contains six structural genes arranged in the order of 3' N-P-M-F-G-L 5'.
Ong, Swee Tin
core  

Encephalitis-Associated Human Metapneumovirus Pneumonia in Adult, Australia

Emerging Infectious Diseases, 2015
Human metapneumovirus pneumonia, most commonly found in children, was diagnosed in an adult with encephalitis. This case suggests that testing for human metapneumovirus RNA in nasopharyngeal aspirate and cerebrospinal fluid samples should be considered ...
Anthony Fok, Cristina Mateevici, Belinda Lin, Ronil V. Chandra, Victor H.T. Chong   +4 more
doaj   +1 more source

Landscape of Prophylactic Strategies Against Human Parainfluenza Virus Type 3

Reviews in Medical Virology, Volume 35, Issue 6, November 2025.
ABSTRACT Human parainfluenza virus‐type 3 (HPIV3) is a respiratory virus responsible for mild illnesses in most of the population and severe illnesses, such as bronchiolitis and pneumonia, in young children, immunocompromised individuals and the elderly.
Clémence Vacher, Julia Dubois, Marie‐Eve Hamelin, Guy Boivin, Manuel Rosa‐Calatrava   +4 more
wiley   +1 more source

Molecular detection and phylogenetic analysis of Peste des petits ruminants virus circulating in small ruminants in eastern Amhara region, Ethiopia [PDF]

, 2019
Background: Peste des Petits Ruminants (PPR) is a severe, highly infectious and fatal viral disease of small ruminants. Four lineages of PPR virus have been identified globally based on sequence analysis of the nucleoprotein (N) and fusion (F) gene.
Abdi, Reta D., Alemu, Biruk, Asfaw, Wondwoson, Belayneh, Rediet, Gari, Getachew, Kidane, Menbere, Kwiatek, Olivier, Libeau, Geneviève, Siraw, Bewuket, Wieland, Barbara   +9 more
core   +1 more source

Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Its Implications for Prophylactic and Therapeutic Pharmaceuticals

MedComm, Volume 6, Issue 10, October 2025.
Respiratory syncytial virus (RSV) causes substantial global morbidity, particularly in infants and elderly populations. This review summarizes key viral pathogenesis mechanisms and highlights recent advances in both prophylactic (vaccines, antibodies) and therapeutic (antiviral agents) strategies against RSV.
Xiaowen Liang, Yue Yin, Yuanlong Lin, Shiman Chen, Qi Qian, Jing Yuan, Liuqing Yang, Yang Yang   +7 more
wiley   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati, Sahar Ghoflchi, Pejman Hosseinzadeh, Sobhan Pouramini, Hossein Hosseini, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

Cell receptor-independent infection by a neurotropic murine coronavirus. [PDF]

, 1992
The cellular receptors for a coronavirus, mouse hepatitis virus (MHV), have been recently identified as one or more members of the carcinoembryonic antigen (CEA) family. The neurotropic JHM strain of MHV (MHV-JHM) possesses a highly fusogenic surface (S)
Buchmeier, MJ, Gallagher, TM, Perlman, S
core  

Sulphated polysaccharides from Ulva clathrata and Cladosiphon okamuranus seaweeds both inhibit viral attachment/entry and cell-cell fusion, in NDV infection [PDF]

, 2015
Sulphated polysaccharides (SP) extracted from seaweeds have antiviral properties and are much less cytotoxic than conventional drugs, but little is known about their mode of action.
Cristina Rodríguez-Padilla, Denis Ricque-Marie, Edgar Mendoza-Gamboa, Jean-François Sassi, José Alberto Aguilar-Briseño, Laura María Trejo-Avila, Lucia Elizabeth Cruz-Suarez, Pablo Zapata-Benavides   +7 more
core   +3 more sources