Results 101 to 110 of about 45,580 (269)

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

The Journal of Pathology, EarlyView.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti, Martina Brigida Romanello, Luca Agnelli, Matteo Orlandi, Luca Bertoli, Sara Picinoli, Irene Pezzali, Giulio Eugenio Mandelli, Daniela Medicina, Giovanni Ribaudo, Adele Busico, Elena Conca, Vilma Pellegrini, Piera Balzarini, Daniele Gallucci, Anna Di Matteo, Davide Lombardi, Claudia Ghigna, Giancarlo Pruneri, Alessandra Gianoncelli, Marzia Rossato, William Vermi   +21 more
wiley   +1 more source

Morphometric and Volumetric Measurements of the Paranasal Sinuses among the population of the Bareilly region [PDF]

, 2022
Background: In the field of sinus surgery and anatomy, the size and shape of the paranasal sinuses vary widely. The volume of paranasal sinuses offers more accurate values and closest to their natural measurements and contributes to diagnosing sinus ...
Sarangdhar Kumar, Rakesh Gupta, Lalit Kumar   +2 more
core  

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Correlation between Pre-Operative CT Scan and Intra Operative Endoscopic Findings in Functional Endoscopic Sinus Surgery

Global Journal of Medicine and Public Health
Introduction Paranasal sinuses are the air containing spaces in skull that include maxillary, ethmoid, frontal and sphenoid sinuses. The nasal passage and paranasal sinuses diseases and conditions range from sinusitis, polyps other inflammations to ...
Amol Khale, Shweta Baviskar, Saima Khan, Pooja Baviskar   +3 more
doaj  

A case of mucocele infiltrate to orbit and frontal lobe

Turkish Archives of Otorhinolaryngology, 2012
Mucocele is slow-growing and locally aggressive lesion of the paranasal sinuses. Mucoceles of the paranasal sinuses most commonly occur in the frontal, and ethmoidal sinuses.
Selahattin Tuğrul
doaj   +1 more source

Imaging of the paediatric paranasal sinuses

, 2013
Sinus development is a dynamic process in children, and appropriate imaging is necessary to adequately demonstrate pathology in our vulnerable paediatric population. The paediatric paranasal sinuses are affected by a wide spectrum of conditions including
Aadil Ahmed
core   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan, Brian Sheng Yep Yeo, Manish Warrier, Jun He Chan, Lu Hui Png, Shuhui Xu, Kimberley LiQin Kiong, Edward C. Kuan, Tze Choong Charn, Neville Wei Yang Teo   +9 more
wiley   +1 more source

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Development of the paranasal sinuses in children.

, 1997
The development of computed tomography and functional endoscopic sinus surgery has improved diagnosis and management of sinusitis. It has also renewed interest in the developmental anatomy of the paranasal sinuses.
Medina, J, Hernandez, H, Bilaniuk, L, Tom, L W   +3 more
core   +1 more source