Results 131 to 140 of about 62,191 (215)
POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley +1 more source
Gephyrin Neurological Autoimmunity
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano +10 more
wiley +1 more source
Background N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a rare neurological autoimmune disease with severe neuropsychiatric symptoms during the acute phase.
Ole Jonas Boeken +13 more
doaj +1 more source
ABSTRACT An anterior mediastinal mass in infants can present with life‐threatening complications due to airway and vascular compression. We report a six‐month‐old infant with a mature teratoma presenting as mediastinal mass syndrome, highlighting the diagnostic challenges and anesthetic risks involved.
Ghamar Taj Khanbabaee +6 more
wiley +1 more source
Pregnancy alters haematologic and inflammatory profiles, potentially masking ovarian cancer. Integrating trimester‐specific NLR, PLR, SII, CRP, CA‐125, haemoglobin, platelet dynamics, and imaging may improve risk stratification. Multimodal biomarkers, longitudinal monitoring, and multidisciplinary assessment can support earlier detection and ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta +2 more
wiley +1 more source
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Generalized granuloma annulare heralding relapse of non-Hodgkin lymphoma
Sarah A. King, MEng +4 more
doaj +1 more source
Giant Intrapulmonary Solitary Fibrous Tumour With a Possible Liver Metastasis: A Rare Case
A 57‐year‐old woman presented with a giant intrapulmonary solitary fibrous tumour (SFT) that progressed from a large left lower lobe mass to extensive thoracic disease with cardiac displacement, pericardial effusion and a hepatic lesion suspicious for metastasis.
Desdiani Desdiani +3 more
wiley +1 more source
Paraneoplastic pemphigus and reported, identified underlying diseases [PDF]
Introduction: Pemphigus is a rare group of autoimmune diseases that promote development of various skin eruptions, the most commonly it presents with blisters.
Paweł Iwańczuk
core

