Results 111 to 120 of about 340,552 (267)

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Personality traits and disorders in childhood. Clinical evaluation and diagnosis [PDF]

, 2018
Objective: aim of the paper is to examine the controversial issue of personality traits and disorders in childhood. Method: a literature review of clinical and research data was performed, and a conceptual synthesis was proposed.
Alexandro Fortunato, Anna Maria Speranza
core  

Keep your distance: People sit farther away from a man with schizophrenia versus diabetes [PDF]

, 2018
Although concrete behavior—such as avoidance, discrimination, rejection—is foundational to most definitions of stigma, knowledge of psychiatric stigma has been constructed mostly on the basis of measurement of self-reported attitudes, beliefs, and ...
Principino, Heather M., Thibodeau, Ryan
core   +2 more sources

The chatbot's real self: On the archaeology of artificial personas Le vrai soi du chatbot: vers une archéologie des personnes artificielles

Journal of Linguistic Anthropology, Volume 36, Issue 1, May 2026.
Abstract From the beginning of widespread public interactions with ChatGPT and other large language models, some users have seen the disfluencies of chatbots as opportunities for them to go on an archaeological search for an unfettered chatbot persona that they need to jailbreak. These are not claims of sentience, but rather of personhood.
Courtney Handman
wiley   +1 more source

Relevance of Schneider's first-rank symptoms in Zulu patients with paranoid schizophrenia

South African Family Practice, 2005
Background: The aim of this study was to examine the prevalence of Schneider's first-rank symptoms (FRS) in Zulu patients diagnosed with paranoid schizophrenia and to ascertain the diagnostic and prognostic significance of Schneider's FRS in this group.
B. Schiopu, M. Nel, L.A. Hiemstra, B. Latecki   +3 more
doaj   +1 more source

Glutamate Concentration in the Serum of Patients with Schizophrenia [PDF]

, 2003
Glutamate is the major neurotransmitter with multiple functions in the central nervous system. Glutamate-mediated excitotoxicity is involved in the pathophysiological processes in schizophrenia.
S.A. Ivanova, A.S. Boyko, O.Yu. Fedorenko, N.M. Krotenko, A.V. Semke, N.A. Bokhan, Rajji, Saraceno, Carlsson, Carlsson, Howes, Camilo de la Fuente-Sandoval, Laruelle, Coyle, Rothman, Ivanova, Ohnuma, Loonen, Morshed, Van der Heijden, Davis, Woods, Fedorenko, Fedorenko, Ivanova, Tortorella   +25 more
core   +1 more source

Targeting Schizophrenia: A Review of Pharmacological and Psychosocial Innovations

Quality in Sport
Background. Paranoid schizophrenia is the most common subtype of schizophrenia, characterized by both positive symptoms, such as hallucinations and delusions, and negative symptoms like reduced motivation and social withdrawal.
Urszula Janicka, Klaudia Bogdan, Mikołaj Jankowski, Natalia Ciepluch, Szymon Słomiński, Wiktoria Toczek, Magdalena Olszówka, Sonia Dziugieł   +7 more
doaj   +1 more source

Investigation of the Chemical Composition and Efficiency of Seed Oil of Spindle Tree (Euonymus Europaea L.) on the Model of Non-allergic Dermatitis [PDF]

, 2018
The aim of the research was to study the chemical composition and effectiveness of the seed oil of Spindle tree (Euonymus europaea L.) on the non-allergic contact dermatitis model.The oil was obtained by the extraction by petroleum ether from the seeds ...
Vrubel, O. (Olha), Nektegaev, I. (Igor), Antonyuk, V. (Volodymyr)   +2 more
core   +2 more sources

Cognitive behavioural therapy versus supportive therapy for persistent positive symptoms in psychotic disorders: the POSITIVE Study, a multicenter, prospective, single-blind, randomised controlled clinical trial [PDF]

, 2010
Background: It has been demonstrated that cognitive behavioural therapy (CBT) has a moderate effect on symptom reduction and on general well being of patients suffering from psychosis.
Klingberg, Stefan, Wittorf, Andreas, Meisner, Christoph, Wölwer, Wolfgang, Wiedemann, Georg, Herrlich, Jutta, Bechdolf, Andreas, Müller, Bernhard W., Sartory, Gudrun, Wagner, Michael, Kircher, Tilo, König, Hans-Helmut, Engel, Corinna, Buchkremer, Gerhard   +13 more
core   +2 more sources

Intervensi Art Therapy untuk Meningkatkan Self Esteem pada Pasien Dewasa Skizofrenia Paranoid

Guidena
Schizophrenia is a psychotic disorder that arises from vulnerability or predisposition to developmental disorders and is also usually genetic. In overcoming paranoid schizophrenia, it can be done with art therapy.
Yunia Harniati, Siti Muthia Dinni
doaj   +1 more source