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Paraproteinemia and neuropathy

Neurological Sciences, 2021
Paraproteinemia is associated with different peripheral neuropathies. The major causes of neuropathy correlated with paraproteinemia are the deposition of immunoglobulin in the myelin, represented by anti-myelin-associated glycoprotein (MAG) neuropathy; deposition of immunoglobulin or its fragment in the interstitium, represented by immunoglobulin ...
Haruki Koike, Masahisa Katsuno
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Plasmapheresis in paraproteinemia

Blut, 1985
Indications, results, techniques, laboratory monitoring and complications of therapeutic plasmapheresis in patients with symptomatic paraproteinemia are reviewed. In paraproteinemia associated with severe complications plasma-pheresis has been used successfully as an emergency treatment, as a treatment that reduces temporarily the paraprotein level ...
H H, Euler, N, Schmitz, H, Löffler
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Bone and paraproteinemias

Current Opinion in Supportive & Palliative Care, 2010
Bone has always been considered a target organ for neoplastic disorder. This review analyzed the close interaction between bone microenvironment and paraproteinemias.Paraproteinemias are a group of disorders characterized by the presence of a monoclonal protein measured in the blood or urine.
Maurizio, Zangari   +2 more
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Paraproteinemia and neoplasia

La Ricerca in Clinica e in Laboratorio, 1985
According to the various case series, both myelomatous and non-myelomatous paraproteinemias are associated with a second malignant neoplasia in a frequency that ranges between 10 and 22%. This association, with a frequency higher than that statistically expected, is 2 to 4 times higher when compared to the association between two tumors of other origin.
L, Bonomo, F, Dammacco, A, Miglietta
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Paraproteinemia and neuropathy

Current Opinion in Neurology, 1999
Paraprotein-associated neuropathies are a diverse group of disorders. The pathogenesis of many of them is poorly understood. Treatments have usually consisted of plasma exchange, corticosteroids, intravenous immunoglobulin, and other immunosuppressive therapies. Response to treatment has varied from good to very poor. Most recent work in this field has
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Idiopathic Paraproteinemia

The Journal of Immunology, 1979
Abstract Transplantation experiments in the C57BL/KaLwRij mouse model of idiopathic paraproteinemia (IP) showed that an IP-producing clone can be further propagated in young, lethally irradiated mice and also equally as well in nonirradiated recipients by a bone marrow and/or spleen cell transfer.
Jiri Radl   +3 more
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Necrobiotic xanthogranuloma with paraproteinemia

Journal of the American Academy of Dermatology, 1980
Eight patients had multiple xanthomatous plaques and subcutaneous nodules that had a predilection for the periorbital area, flexures, and trunk and that tended to ulcerate. Skin biopsy specimens showed a combination of xanthogranulomatous nodules with necrobiosis.
S, Kossard, R K, Winkelmann
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Neuropathies Associated with Paraproteinemia

New England Journal of Medicine, 1998
A number of common disorders of the peripheral nervous system, termed paraproteinemic neuropathies, are closely connected with the presence of excessive amounts of an abnormal immunoglobulin in the blood. These immunoglobulins can be detected by immunoelectrophoresis or the more sensitive immunofixation test.
A H, Ropper, K C, Gorson
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Motor neuron disease and paraproteinemia

Neurology, 1987
We studied two patients with motor neuron disease and paraproteinemia. One had amyotrophic lateral sclerosis (ALS) and IgG lambda monoclonal gammopathy. The second had slowly progressive muscular atrophy and an IgM kappa paraprotein, followed by a biclonal gammopathy when an IgA kappa paraprotein appeared.
S, Rudnicki   +5 more
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HIV-Related Oligoclonal Paraproteinemia

JAMA: The Journal of the American Medical Association, 1987
To the Editor.— Kouns et al 1 recently reported the presence of oligoclonal banding in the serum of patients with antibody to the human immunodeficiency virus (HIV). They state that such a finding is rare in other patients and suggest demonstration of oligoclonal banding as a surrogate test for HIV exposure.
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