Results 31 to 40 of about 26,237 (171)

Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis

open access: yesOpen Biology, 2022
The zinc restriction and zinc toxicity are part of host defence, called nutritional immunity. The crucial role of zinc homeostasis in microbial survival within a host is established, but little is known about these processes in the opportunistic human ...
Tamás Takács   +6 more
doaj   +1 more source

Chemical Profiling, Box-Behnken Optimisation, Antimicrobial Activity, and Molecular Docking Study of Z-Ligustilide Rich Essential Oil From Himalayan Angelica glauca Edgew. [PDF]

open access: yesChem Biodivers
ABSTRACT Angelica glauca Edgew., a high‐altitude Himalayan medicinal plant, is an important source of bioactive essential oil rich in phthalide derivatives. The present study investigated the influence of environmental conditions and extraction parameters on essential oil yield and chemical composition, with particular emphasis on Z‐ligustilide ...
Bisht BS   +6 more
europepmc   +2 more sources

Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans.

open access: yesPLoS Pathogens, 2014
Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CTG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence properties of C.
Linda M Holland   +10 more
doaj   +1 more source

Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants

open access: yesJournal of Fungi, 2023
Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also
Joana Branco   +2 more
doaj   +1 more source

Standardization of polymerase chain reaction for detection of fluconazole resistance targeting Y132F mutation in ERG11 gene in Candida parapsilosis [PDF]

open access: yesCurrent Medical Mycology
Background and Purpose: Candida parapsilosis is the third most commonly isolated species from candidemia patients admitted to Indian intensive care units.
Kanagasabapathi Karthika   +3 more
doaj   +1 more source

First report of monomicrobial Candida parapsilosis necrotizing fasciitis

open access: yes, 2016
Candida parapsilosis is an emerging pathogen worldwide. It commonly causes soft tissue infection; however, to our knowledge there has been no previous report of monomicrobial necrotizing soft tissue infection (NSTI) secondary to C. parapsilosis.
Playford, EG   +5 more
core   +1 more source

Specific pathways mediating inflammasome activation by Candida parapsilosis [PDF]

open access: yes, 2017
Candida albicans and C. parapsilosis are human pathogens causing severe infections. The NLRP3 inflammasome plays a crucial role in host defence against C. albicans, but it has been previously unknown whether C. parapsilosis activates this complex.
Adél Tóth   +5 more
core   +3 more sources

Design of species-specific primers for rapid detection and identification of Candida parapsilosis sensu stricto

open access: yesActa Biologica Slovenica, 2020
Candida species are the cause of approximately two million cases of candidiasis yearly worldwide, and are frequently involved in life-threatening infections.
Monika Novak Babič, Nina Gunde-Cimerman
doaj   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

open access: yesVIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu   +11 more
wiley   +1 more source

Candida parapsilosis secreted lipase as an important virulence factor [PDF]

open access: yes, 2016
The prevalence of Candida parapsilosis, an opportunistic human pathogenic fungal species, is increasing at an alarming rate in the hospital environment. Patients at risk for C.
Toth, Adel   +7 more
core   +1 more source

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