Results 41 to 50 of about 11,470 (289)

Dendritic cell-mediated vaccination relies on interleukin-4 receptor signaling to avoid tissue damage after Leishmania major infection of BALB/c mice. [PDF]

PLoS Neglected Tropical Diseases, 2012
Prevention of tissue damages at the site of Leishmania major inoculation can be achieved if the BALB/c mice are systemically given L. major antigen (LmAg)-loaded bone marrow-derived dendritic cells (DC) that had been exposed to CpG-containing ...
Anita Masic, Ramona Hurdayal, Natalie E Nieuwenhuizen, Frank Brombacher, Heidrun Moll   +4 more
doaj   +1 more source

Climate change promotes parasitism in a coral symbiosis. [PDF]

, 2018
Coastal oceans are increasingly eutrophic, warm and acidic through the addition of anthropogenic nitrogen and carbon, respectively. Among the most sensitive taxa to these changes are scleractinian corals, which engineer the most biodiverse ecosystems on ...
AE Douglas, AG Grottoli, AL Tansik, C Chen, Christopher J. Freeman, D Tchernov, D Yellowlees, David M. Baker, DM Baker, DT Pettay, DW Kemp, EC Franklin, EV Kennedy, F Marubini, FA Al-Horani, I Fagoonee, I Nordemar, J Wiedenmann, Jane C.Y. Wong, JR Zaneveld, KB Strychar, L Ezzat, M Stat, Marilyn L. Fogel, ME Warner, MP Lesser, N Knowlton, Nancy Knowlton, NC Johnson, NE Cantin, O Hoegh-Guldberg, PG Falkowski, PJ Ralph, R Cunning, R Cunning, R Grover, R Rowan, RA Aronson, RL Vega Thurber, SA Wooldridge, SA Wooldridge, SA Wooldridge, SA Wooldridge, SA Wooldridge, Shelby E. McIlroy, SL Coles, SW Jeffrey, T LaJeunesse, T Tomasik, TP Hughes, V Grégoire, V Weis, WK Fitt   +52 more
core   +1 more source

A case of silent invasion : citizen science confirms the presence of Harmonia axyridis (Coleoptera, Coccinellidae) in Central America [PDF]

, 2019
Harmonia axyridis (Coleoptera, Coccinellidae) is a globally invasive ladybird. It has been intentionally introduced in many countries as a biological control agent, whereas it has been unintentionally released in many others.
Haelewaters, Danny, Hiller, Thomas
core   +1 more source

Identification and characterization of the Plasmodium vivax thrombospondin-related apical merozoite protein

Malaria Journal, 2010
Background Malaria caused by Plasmodium vivax is a major public health problem worldwide that affects 70-80 million people in the Middle East, Asia, Western Pacific, South America and the Caribbean.
Villarreal-Gonzalez Silvana, Moreno-Perez Darwin A, Angel Diana I, Mongui Alvaro, Almonacid Hannia, Vanegas Magnolia, Patarroyo Manuel A   +6 more
doaj   +1 more source

The hospitality phenomenon: philosophical enlightenment? [PDF]

, 2007
The emergent paradigm of hospitality studies does not have a coherent philosophical foundation. In seeking to identify a philosophy of hospitality this paper explores Derrida's contribution, along with other writers in philosophy and postcolonial theory,
Conrad Lashley, Kevin D. O'Gorman
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]

, 2017
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson, Andrade-Neto, Antoine, Bansal, Berman, Blanchette-Mackie, Burack, Carstea, Carvalho, Chakraborty, Chattopadhyay, Collins, Coombs, Coppens, De Cicco, Desvergne, Duclos, Edwards, Ehrenman, Fernandes, Ghosh, Ghosh, Ghosh, Ginger, Ginger, Goldstein, Groener, Hamid, Hart, Ikonen, Infante, Johndrow, Kima, Kima, Kok, Kwon, Lal, Lecoeur, Lippuner, Livak, Majumder, Maxfield, McIntosh, Misslitz, Naureckiene, Neufeld, Osorio y Fortea, Ovalle-Bracho, Paape, Paape, Pereira, Portugal, Pucadyil, Rabhi, Redgrave, Roberts, Rosenzweig, Rub, Russell, Saunders, Sen, Shamshiev, Soares, Sorensen, Tetley, Tewary, Tontonoz, Weinheber   +67 more
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii [PDF]

, 2018
Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes ...
Astegno, A., Dominici, P, Fruncillo, S, Janson, G, Maresi, E, Paiardini, A, Vallone, R   +6 more
core   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source