Results 131 to 140 of about 60,049 (296)
Workflow of current study. ABSTRACT Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated.
Souleymane Magagi Damé+4 more
wiley +1 more source
We assessed the effect of mass azithromycin treatment on malaria parasitemia in a trachoma trial in Niger. Twenty-four study communities received treatment during the wet, high-transmission season.
B. Gaynor+14 more
semanticscholar +1 more source
Evolution of malaria virulence in cross-generation transmission through selective immune pressure [PDF]
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence.
David E. Gurarie
core +2 more sources
Bacterial Outer Membrane Vesicles: From Physics to Clinical
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou+7 more
wiley +1 more source
Synchronous culture of Plasmodium falciparum at high parasitemia levels
This protocol describes a method for preparing cultures of Plasmodium falciparum synchronized at any intraerythrocytic stage. Using this method, around 60% parasitized cells may be obtained. On the basis of Trager and Jensen's original continuous culture method, our approach relies on the use of fresh human blood not older than 2 weeks, a low ...
Azar Radfar+7 more
openaire +3 more sources
African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar+160 more
core +1 more source
Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna+10 more
core +4 more sources
Background: Malaria is one of the most serious and complex health problems in Sub Saharan Africa. Anemia in Children with malaria may require blood transfusion and has been be associated with high mortality rates.
N. austin+4 more
semanticscholar +1 more source
INTRODUCTION: The World Health Organization (WHO) recommends testing of suspected malaria cases before treatment. Malaria rapid diagnostic test (mRDT) has been recommended for this purpose in endemic countries where microscopy is not accessible. However,
Nurudeen Ayobami Adebisi+4 more
doaj +1 more source
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C+14 more
core +2 more sources