Results 131 to 140 of about 60,049 (296)

In Vitro Antiplasmodial Activity and Chemical Composition of Combretum aculeatum, a Medicinal Plant From Niger

open access: yesChemistry &Biodiversity, Volume 22, Issue 6, June 2025.
Workflow of current study. ABSTRACT Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated.
Souleymane Magagi Damé   +4 more
wiley   +1 more source

Impact of mass azithromycin distribution on malaria parasitemia during the low-transmission season in Niger: a cluster-randomized trial.

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2014
We assessed the effect of mass azithromycin treatment on malaria parasitemia in a trachoma trial in Niger. Twenty-four study communities received treatment during the wet, high-transmission season.
B. Gaynor   +14 more
semanticscholar   +1 more source

Evolution of malaria virulence in cross-generation transmission through selective immune pressure [PDF]

open access: yes, 2007
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence.
David E. Gurarie
core   +2 more sources

Bacterial Outer Membrane Vesicles: From Physics to Clinical

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou   +7 more
wiley   +1 more source

Synchronous culture of Plasmodium falciparum at high parasitemia levels

open access: yesNature Protocols, 2009
This protocol describes a method for preparing cultures of Plasmodium falciparum synchronized at any intraerythrocytic stage. Using this method, around 60% parasitized cells may be obtained. On the basis of Trager and Jensen's original continuous culture method, our approach relies on the use of fresh human blood not older than 2 weeks, a low ...
Azar Radfar   +7 more
openaire   +3 more sources

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

open access: yes, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar   +160 more
core   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

open access: yes, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna   +10 more
core   +4 more sources

Prevalence and Severity of Malaria Parasitemia among Children Requiring Emergency Blood Transfusion in a Tertiary Hospital in Imo State, Nigeria

open access: yesAnnals of Medical and Health Sciences Research, 2014
Background: Malaria is one of the most serious and complex health problems in Sub Saharan Africa. Anemia in Children with malaria may require blood transfusion and has been be associated with high mortality rates.
N. austin   +4 more
semanticscholar   +1 more source

Performance of malaria rapid diagnostic test in febrile under-five children at Oni Memorial Children's Hospital in Ibadan, Nigeria, 2016

open access: yesThe Pan African Medical Journal, 2018
INTRODUCTION: The World Health Organization (WHO) recommends testing of suspected malaria cases before treatment. Malaria rapid diagnostic test (mRDT) has been recommended for this purpose in endemic countries where microscopy is not accessible. However,
Nurudeen Ayobami Adebisi   +4 more
doaj   +1 more source

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]

open access: yes, 2007
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C   +14 more
core   +2 more sources

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