Results 131 to 140 of about 60,876 (303)
Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.Dogs are major reservoirs of Trypanosoma cruzi in Texas, United States. This study evaluated a novel Tc‐24 recombinant antigen ELISA for the serologic detection of Chagas disease in dogs and found it to have high sensitivity and specificity compared to existing commercial tests. The Tc‐24 Chagas ELISA provides a reliable tool for enhanced canine Chagas
Rojelio Mejia +7 more
wiley +1 more source
Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
, 2017 Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
core +1 more source
Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives
ChemMedChem, Volume 20, Issue 16, August 16, 2025.Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi +7 more
wiley +1 more source
In vitro and In vivo Antiplasmodial of Stem Bark Extract of Garcinia husor
Hayati Journal of Biosciences, 2019 Garcinia husor is one of the folk medicines in Maluku-Indonesia. This species has been used for the treatmet of Malaria disease. The phytochemical contents and antiplasmodial activity not reported yet.
Healthy Kainama +4 more
doaj +1 more source
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, Volume 5, Issue 8, August 2025.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
Journal of Infectious Diseases, 2013 Background. Current malaria diagnostic tests, including microscopy and antigen-detecting rapid tests, cannot reliably detect low-density infections. Molecular methods such as polymerase chain reaction (PCR) are highly sensitive but remain too complex for
Heidi Hopkins +10 more
semanticscholar +1 more source
Archiv der Pharmazie, Volume 358, Issue 8, August 2025.The antiplasmodial properties of a series of fluorinated peptoid‐based histone deacetylase (HDAC) inhibitors were evaluated by screening them for their activity against asexual blood and liver stage malaria parasites and assessing their mammalian cell toxicity, to elucidate structure–activity and structure‐toxicity relationships. Compound 1h emerged as
Nina Reßing +6 more
wiley +1 more source
In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone
Drug Development Research, Volume 86, Issue 5, August 2025.ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp +4 more
wiley +1 more source
Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]
, 2016 Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia +8 more
core +4 more sources
The Diagnostic Performance of a Sysmex XN‐31 Automated Malaria Analyzer vs. Expert Microscopy
International Journal of Laboratory Hematology, Volume 47, Issue 4, Page 613-621, August 2025.ABSTRACT Introduction Malaria is a common and life‐threatening infection. Malaria diagnosis needs to be fast and reliable. Although malaria microscopy is currently the gold standard, it is laborious, requires extensive training, and relies heavily on the proficiency of microscopists.
S. Onsongo +9 more
wiley +1 more source