Results 71 to 80 of about 9,472,164 (402)

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

Identification and genotyping of Enterocytozoon bieneusi in wild Himalayan marmots (Marmota himalayana) and Alashan ground squirrels (Spermophilus alashanicus) in the Qinghai-Tibetan Plateau area (QTPA) of Gansu Province, China

Parasites & Vectors, 2020
Background Enterocytozoon bieneusi is the most frequently detected microsporidian species in humans and animals. Currently, to the best of our knowledge, no information on E. bieneusi infection in Himalayan marmots (Marmota himalayana) and Alashan ground
Jie Xu, Xin Wang, Huaiqi Jing, Shengkui Cao, Xiaofan Zhang, Yanyan Jiang, Jianhai Yin, Jianping Cao, Yujuan Shen   +8 more
doaj   +1 more source

Facing the threat of equine parasitic disease.

Equine Veterinary Journal, 2011
Horses worldwide are exposed to a complex mixture of intestinal parasitic helminths. When burdens are high, these parasites can seriously compromise health and welfare. Some helminth species have an extremely high prevalence and are difficult to control,
J. Matthews
semanticscholar   +1 more source

Animal health in organic livestock systems: a review [PDF]

, 2006
Organic livestock production is a means of food production with a large number of rules directed towards a high status of animal welfare, care for the environment, restricted use of medical drugs and the production of a healthy product without residues ...
Eijck, Drs. Ineke, Kijlstra, Prof. Dr. Aize   +1 more
core  

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Neglected Parasitic Infections in the United States: Chagas Disease

American Journal of Tropical Medicine and Hygiene, 2014
Chagas disease, which is caused by the protozoan parasite Trypanosoma cruzi, can lead to severe cardiac and gastrointestinal disease. Most persons acquire this infection through contact with vector bugs carrying T. cruzi in endemic areas of Latin America.
S. Montgomery, M. Starr, P. Cantey, M. Edwards, S. Meymandi   +4 more
semanticscholar   +1 more source

Saprolegnia on roach (Leuciscus rutilus) and carp (Cyprinus carpio) [Translation from: Acta zool.pathol.Antverpiensia 43 107-123, 1976] [PDF]

, 1979
There is, in nature, as well as in the aquarium, a parasitic disease known as 'mousse' and which attacks predominantly fish. It is caused by Phycomycete fungi, genus Saprolegnia.
Nolard-Tintigner, N.
core  

Detachable and Reusable: Reinforced π‐Ion Film for Modular Synaptic Reservoir Computing

Advanced Materials, EarlyView.
This study presents a reinforced π‐ion film for organic electrochemical transistors (OECTs), addressing the rapid degradation of organic semiconductor layers. By introducing a mesh support and utilizing a scalable solvent exchange method, the π‐ion film enhances detachability and stability.
Gyu Won Woo, Chang Min Lee, Won Woo Lee, Min Ju Jung, Seung Min Lee, Hye Won Lee, Hocheon Yoo, Yong Hee Kim, Eun Kwang Lee   +8 more
wiley   +1 more source

Study roadmap for high-throughput development of easy to use and affordable biomarkers as diagnostics for tropical diseases: a focus on malaria and schistosomiasis

Infectious Diseases of Poverty, 2017
Background Interventions are currently being used against ‘infectious diseases of poverty’, which remain highly debilitating and deadly in most endemic countries, especially malaria, schistosomiasis, echinococcosis and African sleeping sickness. However,
Kokouvi Kassegne, Ting Zhang, Shen-Bo Chen, Bin Xu, Zhi-Sheng Dang, Wang-Ping Deng, Eniola Michael Abe, Hai-Mo Shen, Wei Hu, Takele Geressu Guyo, Solomon Nwaka, Jun-Hu Chen, Xiao-Nong Zhou   +12 more
doaj   +1 more source

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]

, 2015
Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M., Harnett, W., Pineda, M. A., Rodgers, D. T., Suckling, C. J.   +4 more
core   +1 more source