Results 91 to 100 of about 69,971 (258)
Biotechnology Progress, EarlyView.Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi +8 more
wiley +1 more source
Cytoskeleton, EarlyView.ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas +5 more
wiley +1 more source
The Helminth Parasites of Animals and Human Disease [PDF]
Proceedings of the Royal Society of Medicine, 1927 openaire +2 more sources
Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib
Clinical Pharmacology &Therapeutics, EarlyView.Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó +7 more
wiley +1 more source
Veterinary SciencesEquine granulocytic anaplasmosis (EGA) is a tick-borne disease affecting horses worldwide, caused by Anaplasma phagocytophilum. The disease ranges from non-specific clinical signs to fatal outcomes.
Andreea Monica Bogdan +2 more
doaj +1 more source
Ecography, EarlyView.Non‐native species introductions profoundly alter freshwater communities, yet the mechanisms by which non‐native fishes affect native community stability remain unclear. Using a multi‐decadal dataset on fish community composition and abundance collected across France, we quantified native community stability and decomposed this metric into its main ...
Chengzong Tian +5 more
wiley +1 more source
Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective
Equine Veterinary Journal, EarlyView.Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén +8 more
wiley +1 more source
Potential for conflict between urban coyotes and people experiencing unsheltered homelessness
Frontiers in Ecology and the Environment, EarlyView.Across North America, both unsheltered homelessness and human–coyote (Canis latrans) conflict are increasing, but the relationship between these phenomena has not been thoroughly explored. We synthesize literature‐based evidence with anecdotal observations that occurred during a 15‐year study of coyotes in Edmonton, Canada, to describe three likely ...
Sage Raymond +2 more
wiley +1 more source