Results 31 to 40 of about 154,083 (299)

Efficacy of a multivalent vaccine against Fasciola hepatica infection in sheep

Veterinary Research, 2021
In this work we report the protection found in a vaccination trial performed in sheep with two different vaccines composed each one by a cocktail of antigens (rCL1, rPrx, rHDM and rLAP) formulated in two different adjuvants (Montanide ISA 61 VG (G1) and ...
Rafael Zafra, Leandro Buffoni, Raúl Pérez-Caballero, Verónica Molina-Hernández, María T. Ruiz-Campillo, José Pérez, Álvaro Martínez-Moreno, Francisco J. Martínez Moreno   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Chromosomal scale assembly and functional annotation of the apicomplexan parasite Eimeria acervulina

Scientific Data
Apicomplexan parasites are single-celled obligate intracellular eukaryotic organisms that cause significant animal and human disease and pose a substantial health and socioeconomic burden worldwide.
Subodh K. Srivastava, Carolyn C. Parker, Peter C. Thompson, Matthew S. Tucker, Benjamin M. Rosenthal, Asis Khan, Matthew J. Valente, Mark C. Jenkins   +7 more
doaj   +1 more source

Antigen-specific response of CD4+ T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep

Veterinary Research, 2021
The immunomodulatory capacity of F. hepatica antigens is probably one of the main reasons for the development of a driven non-protective Th2 immune response. In this study, we analysed the cellular response of hepatic lymph node cells and CD4+ T cells in
Raúl Pérez-Caballero, F. Javier Martínez-Moreno, Yolanda Corripio-Miyar, Tom N. McNeilly, Krystyna Cwiklinski, John P. Dalton, Rafael Zafra, José Pérez, Álvaro Martínez-Moreno, Leandro Buffoni   +9 more
doaj   +1 more source

Animal health in organic livestock systems: a review [PDF]

, 2006
Organic livestock production is a means of food production with a large number of rules directed towards a high status of animal welfare, care for the environment, restricted use of medical drugs and the production of a healthy product without residues ...
Eijck, Drs. Ineke, Kijlstra, Prof. Dr. Aize   +1 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time-dependent RNA transcriptional profiling of abomasal mucosa in cattle infected with Ostertagia ostertagi

Scientific Data
In this study, we infected Holstein calves with Ostertagia ostertagi stage 3 larvae (L3) and determined gene expression profiles of abomasal fundic and pyloric mucosa by RNA sequencing (RNA-seq) at 3–5, 7–9, 10, and 21 days post-infection (dpi), which ...
Clarissa Boschiero, Ethiopia Beshah, Mariam Bakshi, Peter Thompson, Xiaoping Zhu, George E. Liu, Wenbin Tuo   +6 more
doaj   +1 more source

Effects of Competitive ELISA-Positive Results of Piroplasmosis on the Performance of Endurance Horses

Animals, 2022
Endurance is an increasingly popular equestrian sport. However, in southern Europe, there is a high prevalence of horses that are asymptomatic carriers of equine piroplasmosis (EP), a tick-borne disease that could affect their performance.
Daniel Bravo-Barriga, Francisco J. Serrano-Aguilera, Rafael Barrasa-Rita, Miguel Ángel Habela, Rafael Barrera Chacón, Luis Javier Ezquerra, María Martín-Cuervo   +6 more
doaj   +1 more source

Major animal health problems of market oriented livestock development in Atsbi Womberta woreda, Tigray Regional State [PDF]

, 2010
An attempt was made to study major health problems of livestock in Atsbi womberta Woreda, northern Ethiopia, from December 2006 to April 2007. Questionnaire survey was carried out on 100 livestock owners to collect information on the livestock ...
Abraha, G.G.
core  

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source