Results 141 to 150 of about 403,974 (337)

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

Chemistry &Biodiversity, EarlyView.
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, EarlyView.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Chemical Composition and In Vitro Antibiofilm Action of Varronia curassavica Jacq. (Boraginaceae) Essential Oil: A Promising Natural Agent Against Bacterial Infections

Chemistry &Biodiversity, EarlyView.
ABSTRACT Antimicrobial resistance is an increasing threat to public health, with alarming estimates of mortality rates. In this context, the clinical properties of Varronia curassavica Jacq. are highlighted due to its biological and pharmacological activities.
José Thyálisson da Costa Silva, Gabriel Gonçalves Alencar, Nara Juliana Santos Araújo, Lariza Leisla Leandro Nascimento, Saulo Almeida Menezes, Dhenes Ferreira Antunes, Adrielle Rodrigues Costa, Murilo Felipe Felício, Cicero dos Santos Leandro, Luis Pereira de Morais, Marcos Aurélio Figueirêdo dos Santos, Severino Denicio Gonçalves de Sousa, Julimery Gonçalves Ferreira Macedo, João Pereira da Silva Junior, Ana Carolina Ferreira Araujo, Maísa Freire Cartaxo Pires de Sá, Jacqueline Cosmo Andrade‐Pinheiro, Henrique Douglas Melo Coutinho, José Weverton Almeida‐Bezerra   +18 more
wiley   +1 more source

Characterization and Variability Analysis of Volatile Metabolites From Acer saccharum Leaves From Québec Region

Chemistry &Biodiversity, EarlyView.
ABSTRACT Volatile secondary metabolites in plants can serve as valuable biomarkers for the plant's health, stress response, and pest or disease detection. We have investigated the volatilome of Acer saccharum (sugar maple) leaves using two complementary extraction techniques: headspace‐solid phase micro‐extraction coupled with gas chromatography‐mass ...
Jean‐Christophe Séguin, Chelsea Mahannah, Normand Voyer   +2 more
wiley   +1 more source

Genome Mining Reveals a Novel Nephthenol‐Producing Diterpene Synthase from the Sandfly Lutzomyia Longipalpis

ChemBioChem, EarlyView.
The discovery of a terpene synthase of insect origin that makes the apparently cryptic product nephthenol from geranylgeranyl diphosphate sheds light on hidden biosynthetic potential. Populations of the sandfly, Lutzomyia longipalpis, use the diterpene sobralene as a sex/aggregation pheromone, which is likely produced in the insect through the activity
Charles Ducker, Catherine McKeown, Igor F. P. Da Silva, Isis Torres Souza, John A. Pickett, Antônio E. G. Santana, Neil J. Oldham   +6 more
wiley   +1 more source

Bioactivity profiles of progressively ring‐fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto‐piperazines as anti‐trypanosome agents.

ChemBioChem, Accepted Article.
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan, Mengfan He, Christina M Thomson, Dawn Thompson, Vytautus Kuodis, Terence K. Smith, Sergio Dall'Angelo   +6 more
wiley   +1 more source

Gastroenterology Vol. 4 Peritoneum, Parasitic Diseases and System Interrelationships [PDF]

, 1978
J J Misiewicz
openalex   +1 more source