Results 131 to 140 of about 1,847,937 (304)

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Toxocariasis fact sheet [PDF]

Toxocariasis is a parasitic disease in people caused by infection with a roundworm found in dogs or cats.CS223856-AWhat is toxocariasis? -- Who can get toxocariasis? -- How does someone get toxocariasis? -- What are the symptoms?

core  

Heavy Schistosomiasis Associated With Poor Short-Term Memory and Slower Reaction Times in Tanzania Schoolchildren [PDF]

, 2002
Cross-sectional studies of the relationship between helminth infection and cognitive function can be informative in ways that treatment studies cannot.
Department for Infectious Disease Epidemiology,Imperial College Shool of Medicine,London, Department for Infectious Disease
core  

A Current Conveyor Implementation of Double Differential Amplifier for Active Electrodes

International Journal of Circuit Theory and Applications, EarlyView.
A CCII‐based electronic architecture for surface electromyography (sEMG) signal acquisition is presented. Simulations results demonstrate its potential as an effective analog front‐end for biomedical monitoring applications. ABSTRACT This work presents two transistor‐level solutions to implement a double differential (DD) amplifier by using a current ...
Carla Caruso, Alfio Dario Grasso, Federico N. Guerrero, Gaetano Palumbo   +3 more
wiley   +1 more source

High‐Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples

Cytometry Part A, EarlyView.
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy, Alexander T. Heubeck, Tyanna Stuckey, Veronica Hernandez, Blessing Musgrove, Maia M. Bennett‐Boehm, Troy Torgerson, Peter Skene, Julian Reading   +8 more
wiley   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Potential for conflict between urban coyotes and people experiencing unsheltered homelessness

Frontiers in Ecology and the Environment, EarlyView.
Across North America, both unsheltered homelessness and human–coyote (Canis latrans) conflict are increasing, but the relationship between these phenomena has not been thoroughly explored. We synthesize literature‐based evidence with anecdotal observations that occurred during a 15‐year study of coyotes in Edmonton, Canada, to describe three likely ...
Sage Raymond, Jeff Rose, Colleen Cassady St Clair   +2 more
wiley   +1 more source

Phytochemical Composition and Bioactivity of Elsholtzia strobilifera (Benth.) Benth Essential Oil With Spectral Characterisation of Pinocarvone Using NMR Techniques

Flavour and Fragrance Journal, EarlyView.
Elsholtzia strobilifera (Benth.) EO: in‐depth chemical and biological investigation. ABSTRACT Species of the genus Elsholtzia (Lamiaceae) have been traditionally used in folk medicine and are known for their diverse biological properties. However, the chemical composition and bioactivity of the essential oil from Elsholtzia strobilifera (Benth.) Benth.
Priyanka Bhatt, Pooja Bargali, Gunja Sah, G. C. Shah, Ravendra Kumar, Stefania Garzoli, Maneesha Pathak, Archana N. Sah   +7 more
wiley   +1 more source

Biofilm formation by the global outbreak strain of Mycobacterium chimaera results in significantly reduced efficacy of standard disinfectants

BMC Microbiology
Background In 2013, a global outbreak of Mycobacterium chimaera infections due to contaminated heater-cooler units emerged. This ongoing problem has highlighted the question of whether disinfection recommendations for medical devices containing water ...
Anna Maria Oschmann, Katharina Konrat, Christoph Schaudinn, Genevieve Sohl, Dirk Wagner, Astrid Lewin, Mardjan Arvand   +6 more
doaj   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source