Results 91 to 100 of about 257,672 (214)
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez +7 more
wiley +1 more source
ABSTRACT Background Prolonged standing is common in manufacturing and assembly‐line work and is associated with musculoskeletal discomfort, especially in the lower limbs and spine. The influence of foot posture, morphology, and plantar loading patterns on this discomfort remains unclear.
Alejandro‐Jesús Almenar‐Arasanz +7 more
wiley +1 more source
Free‐Breathing Hepatic Oxygen Extraction Fraction (OEF) Mapping Using Radial GESSE
ABSTRACT Purpose Noninvasive assessment of hepatic oxygenation is relevant for evaluating liver both in acute and long‐term liver pathologies. However, existing methods are limited to single‐slice acquisitions and require breath‐holding. This study aims to develop and evaluate a motion‐robust technique for whole‐liver oxygen extraction fraction (OEF ...
Ke Zhang +9 more
wiley +1 more source
ABSTRACT Bariatric surgery is increasingly performed in adolescents and young adults. Although sleeve gastrectomy preserves intestinal continuity and is often regarded as nutritionally low‐risk, it can still precipitate micronutrient deficiency, and obesity itself predisposes to thiamine deficiency, which can cause both Wernicke encephalopathy and a ...
Altin Kuqo, Floreta Kurti, Erand Llanaj
wiley +1 more source
Proton-density fat fraction (PDFF) of the paraspinal muscles, derived from chemical shift encoding-based water-fat magnetic resonance imaging, has emerged as an important surrogate biomarker in individuals with intervertebral disc disease, osteoporosis ...
Thomas Baum +8 more
doaj +1 more source
ABSTRACT Background Respiratory motion artifacts impair diagnostic accuracy in gadoxetic acid disodium (Gd‐EOB‐DTPA)‐enhanced liver MRI. Conventional verbal pre‐scan breathing training often yields inconsistent patient cooperation and image quality, creating an urgent clinical need for optimized training methods.
Li Mei +7 more
wiley +1 more source
Purpose: The aim of our study was the comparison of active denervation (fibrillation and/or positive sharp wave potentials) in thoracic paraspinal muscles with rectus abdominis in patients with definite amyotrophic lateral sclerosis. Methods: Ninety-five
Koutsoudaki, P. +4 more
core +1 more source
Previous findings showed that IVIM measures in lumbar muscles in response to acute exercise could predict response to exercise‐based rehabilitation in chronic low back pain. Here, we tested this in a larger independent cohort (n = 37), confirming greater increases in muscle diffusion (D) after exercise in those who responded to rehabilitation. However,
Frederique Dupuis +8 more
wiley +1 more source
Mind the gap: Reproducibility of methods for studying paraspinal muscles
Background: We respond to a recent study on Magnetic Resonance Imaging-based measurement of paraspinal muscles in patients with chronic back pain. Methods: We reviewed their methodology with a focus on segmentation tools and observer reliability. Results:
Nayia Aza +2 more
core +1 more source
Targeting driver and structural vertebrae via LLIF is an effective, minimally invasive strategy for ADS. It offers substantial deformity correction, symptom relief, and progressive postoperative self‐correction while significantly reducing surgical trauma compared to traditional long‐segment fusions.
Tianyong Wen +7 more
wiley +1 more source

