Results 71 to 80 of about 161,426 (290)
A Splice‐Region Variant Causes an Atypical Presentation of GNAS Inactivation Disorder
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic variants in GNAS can cause a wide range of diseases including pseudohypoparathyroidism, pseudopseudohypoparathyroidism, McCune‐Albright syndrome, among others. The specific phenotypic features that may be seen are influenced by the variant type and location in the gene, whether it causes loss or gain of function, and whether it is ...
Brandon S. Stone +11 more
wiley +1 more source
Frontiers in Endocrinology, 2021 Parathyroid adenoma is a tumor composed of increased parenchymal tissue, often built-up by chief cells, transitional cells or oncocytic cells arranged in acinar or solid formations.
C. Christofer Juhlin +3 more
doaj +1 more source
Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis [PDF]
, 2019 Background: Etelcalcetide is an intravenous calcimimetic approved for treatment of secondary hyperparathyroidism (sHPT) in patients receiving hemodialysis. Besides lowering parathyroid hormone (PTH), etelcalcetide also significantly reduces fibroblast
Block, Geoffrey A. +9 more
core +1 more source
Phosphatemia is an Independent Prognostic Factor in Amyotrophic Lateral Sclerosis
Annals of Neurology, EarlyView.Objective The objective of this study was to evaluate the prognostic value of several muscle damage biomarkers. Methods Data from Piemonte and Valle d'Aosta Amyotrophic Lateral Sclerosis (PARALS) were considered for this study. Survival was defined as the time from diagnosis to death, tracheostomy, or the censoring date.
Rosario Vasta +18 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
About A Rare Cause Of Primary Hyperparathyroidism [PDF]
, 2011 Introduction: Primary hyperparathyroïdism is observed in 35 to 44 subjects/ 100000 persons. The increased production of parathyroid hormones is secondary to primary glandular modifications consisting mainly in adenomas.
Mona Mlika, Zidi-Moaffak Y , Lakhoua Y, Farah F, Kourda N, Ben Abdallah N, Zermani R, Baltagi-Ben Jilani S , Int J Cur Bio Med Sci.
core
PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases. [PDF]
, 2018 Metastatic breast cancer (BrCa) is currently incurable despite great improvements in treatment of primary BrCa. The incidence of skeletal metastases in advanced BrCa occurs up to 70%.
Wang, Bin, Yang, Yanmei
core +2 more sources
Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis
Arthritis &Rheumatology, EarlyView.Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley +1 more source
Parathyroid hormone secretion is controlled by both ionized calcium and phosphate during exercise and recovery in men [PDF]
, 2016 Context: The mechanism by which PTH is controlled during and after exercise is poorly understood due to insufficient temporal frequency of measurements.
Currell, Kevin +7 more
core +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian +5 more
wiley +1 more source