Results 71 to 80 of about 89,012 (243)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang +7 more
wiley +1 more source
BiomedicinesBackground: Papillary thyroid carcinoma in the isthmus (PTCI) remains a subject of surgical debate due to its unique anatomical location and reportedly more aggressive behavior, including higher rates of lymph node metastasis, multifocality ...
Yuhan Jiang +4 more
doaj +1 more source
ACR‐TIRADS Institution and Effect on Thyroid Surgeries in Veterans: A 10‐Year Retrospective Study
The Laryngoscope, EarlyView.Following analysis of the adoption of ACR TI‐RADS at the VA Northern California Healthcare System, the number of thyroid ultrasounds and FNAs increased substantially, while the total number of thyroid surgeries remained relatively stable. Surgical practice trends towards more selective and less‐invasive management, with fewer total thyroidectomies for ...
Isabella W. Leon +4 more
wiley +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Med Research, EarlyView.White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Pediatric Investigation, EarlyView.This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu +6 more
wiley +1 more source
Precision Medical Sciences, EarlyView.Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain +4 more
wiley +1 more source