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Background. Parathyroid carcinoma is the least frequent malignancy among endocrine tumors. In the most reported series of patients with primary hyperparathyroidism the incidence of carcinoma is less than 1%.
Filipović Aleksandar +3 more
doaj +10 more sources
Asymptomatic giant intrathyroid parathyroid carcinoma and common parathyroid carcinoma: two case reports and literature review [PDF]
BackgroundParathyroid carcinoma (PC) is a rare, slow-growing but locally aggressive endocrine malignant tumor. Its clinical diagnosis is difficult, especially intrathyroid parathyroid carcinoma with atypical or asymptomatic symptoms.
Riqiang Liu +3 more
doaj +3 more sources
Although parathyroid neoplasms are common and cause primary hyperparathyroidism, parathyroid carcinoma is a rare entity. At times it can be difficult to diagnose. Patients with parathyroid carcinoma usually present with profound symptoms of hyperparathyroidism and highly elevated serum calcium and parathyroid hormone (PTH) levels.
A S, Khurana, M, Munjal, M, Narad
core +9 more sources
Parathyroid carcinoma is a rare endocrine malignancy. The reported incidence is from 0.5 to 5% of primary hyperparathyroidism cases in various series. The cause is unknown, but clinical correlations with different genetic syndromes exist. Mutations in the HPRT2 gene seem to play a significant role in the pathogenesis of this disease.
exaly +5 more sources
Discordant sestamibi uptake in synchronous parathyroid carcinoma and adenoma [PDF]
The simultaneous occurrence of parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma is exceptionally rare. Herein, we present an uncommon case in which the right malignant parathyroid lesion was 99mTc-MIBI-negative and the ...
Qian Wang +4 more
doaj +2 more sources
Parathyroid carcinoma co-occurring with parathyroid adenoma and papillary thyroid carcinoma: a rare case report with comprehensive literature review [PDF]
Parathyroid carcinoma is a rare endocrine malignancy with unclear etiology, and its clinical manifestations are often difficult to distinguish from parathyroid adenoma.
Junming Liu, Jingting Li, Yantao Fu
doaj +2 more sources
Synchronous parathyroid carcinoma and papillary thyroid carcinoma
The simultaneous occurrence of parathyroid carcinoma and nonmedullary thyroid carcinoma is unusual. We report the case of 60‐year‐old woman who was found to have concurrent parathyroid carcinoma with severe clinical manifestations of primary ...
Ibtissem Ben Nacef +8 more
doaj +1 more source
Key Clinical Message Rare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection.
Alex Mremi +4 more
doaj +1 more source
Nineteen cases of parathyroid carcinoma in patients with multiple endocrine neoplasia type 1 have been reported in the literature, of which 11 carry an inactivating germline mutation in the MEN1 gene.
Sara Lomelino Pinheiro +5 more
doaj +1 more source
Background Parathyroid carcinoma is a rare endocrine malignancy, rarer when synchronous with a non medullary well differentiated thyroid carcinoma. Parathyroid carcinoma accounts of 0.005% of all malignant tumors and it is responsible for less than 1% of
Nadia De Falco +11 more
doaj +1 more source

