Results 91 to 100 of about 370,756 (269)

Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma

International Journal of Endocrinology, 2020
Objective. Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or ...
Luigia Cinque, Flavia Pugliese, Celeste Clemente, Stefano Castellana, Maria Pia Leone, Danilo de Martino, Teresa Balsamo, Claudia Battista, Tommaso Biagini, Paolo Graziano, Marco Castori, Alfredo Scillitani, Vito Guarnieri   +12 more
doaj   +1 more source

Metabolic and functional imaging employment in the differentiation of brown tumors from bone metastases in a case of primary papillary thyroid cancer and parathyroid adenoma: case report

Journal of the Egyptian National Cancer Institute, 2021
Background Brown tumors are benign osteoclastic bone lesions encountered in patients with hyperparathyroidism. These tumors may demonstrate aggressive, destructive features in the skeleton and imitate metastatic bone lesions, particularly in patients ...
Ula Al-Rasheed, Fareed Barakat, Akram Al-Ibraheem   +2 more
doaj   +1 more source

A rare combination of tumor-induced osteomalacia caused by sinonasal glomangiopericytoma and coexisting parathyroid adenoma: case report and literature review

BMC Endocrine Disorders, 2022
Background Tumor-induced osteomalacia (TIO) is a rare, acquired disease of renal phosphate wasting and disturbed vitamin D homeostasis as a result of the action of a phosphaturic protein – FGF-23, produced by a neoplasm.
Agnieszka Brociek-Piłczyńska, D. Brodowska-Kania, Kornel Szczygielski, M. Lorent, G. Zieliński, P. Kowalewski, D. Jurkiewicz   +6 more
semanticscholar   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Orthopaedic Surgery, Volume 15, Issue 1, Page 256-265, January 2023., 2023
In patients with femoral head necrosis, strong positive reaction of LC3‐II could be identified in the cytoplasm of osteoclasts, in significant contrast to the background. A trabecula was surrounded by several LC3‐II‐positive osteoclasts, which were in close contact with the trabecula.
Bo Liu, Feng Gao, Xiaofei Xiu, Tao Wu, Zeming Liu, Bingshi Zhang, Sikai Liu, Yongtai Han   +7 more
wiley   +1 more source

A patient with femoral osteitis fibrosa cystica mimicking bone neoplasm: a case report

BMC Musculoskeletal Disorders, 2022
Background Osteitis fibrosa cystica is a rare, benign and osteolytic lesion attributed to hyperparathyroidism. The high level of parathyroid hormone cause rapid bone loss.
Xiao-long Xu, Cuicui Yang, Sheng-jun Lu, Hong-hui Pei, Shun-guang Chen, Quan-ming Liao   +5 more
semanticscholar   +1 more source

Identification of NIBAN2‐Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis

Advanced Science, EarlyView.
NIBAN2 interacts with the HNRNPU‐cored spliceosome complex and alters its components to regulate the alternative splicing of RUNX2, which ultimately cause an increase in functional RUNX2 (nuclear localization sequence complete) but a decrease in dysfunctional Runx2 (exon 6‐exclusive) isoforms to reinforce osteoblast differentiation.
Sheng Zhang, Zhiqiang Yang, Yuanlong Xie, Yufeng Zhang, Zhe Chen, Xuan Lv, Zhouming Deng, Zan Huang, Lin Cai, Renxiong Wei   +9 more
wiley   +1 more source

Intrathyroidal Parathyroid Carcinoma: An Atypical Thyroid Lesion

Frontiers in Endocrinology, 2018
Parathyroid carcinoma is a rare endocrine malignancy that is typically difficult to diagnose at presentation. Here, we report a 63 year-old man who had symptomatic hypercalcemia.
Noran Alharbi, Noran Alharbi, Sylvia L. Asa, Marta Szybowska, Raymond H. Kim, Raymond H. Kim, Shereen Ezzat   +6 more
doaj   +1 more source

Hypercalcemia in the Presence of an Ectopic Mediastinal Mass

Journal of Primary Care & Community Health, 2020
A 72-year-old gentleman who presented to the outpatient clinic for a preventive health appointment with symptoms of depression and fatigue was found to have persistent hypercalcemia on routine laboratory monitoring.
Robert K. Strother, Matthew Meunier MD
doaj   +1 more source

Secondary hyperparathyroidism induced parathyroid adenoma masquerading as a solitary thyroid nodule-a case report

International Journal of Otorhinolaryngology and Head and Neck Surgery, 2022
Parathyroid adenoma is associated with both primary and secondary hyperparathyroidism (SHPT). Identification of the adenoma requires a combination of clinical evidence, imaging information and cytological findings due to the challenging distinction ...
M. Yadav, P. Sahu, Sanjay Kumar, Roohie Singh, P. Paramasivam, N. Dogra   +5 more
semanticscholar   +1 more source