Results 11 to 20 of about 25,264 (186)

Malignant neoplasms and parathyroid adenoma [PDF]

Cancer, 1971
Isolated publications note the association of thyroid carcinoma, thymoma, and parathyroid adenoma with malignancies of other organs or systems. Of 166 patients with histologically proven parathyroid adenomas, 42% of those found at autopsy and 16% of such patients with parathyroidectomy and no autopsy had such malignancies. Seventy-five similar patients
L, Kaplan, A D, Katz, C, Ben-Isaac, S G, Massry   +3 more
openaire   +2 more sources

Primary Hyperparathyroidism With Brown Tumor-A Case Mistaken as Non-Ossifying Fibroma Resolved by Biochemical and Radiological Correlation. [PDF]

Clin Case Rep
ABSTRACT Primary hyperparathyroidism (PHPT) is uncommon in the pediatric population and rarely presents with overt skeletal complications such as brown tumors. This case study describes a 16‐year‐old female who initially presented with abdominal pain and was subsequently found to have severe hypercalcemia (serum calcium 16.4 mg/dL) and markedly ...
Regmi D, Bhatta U, Bhattarai M, Jha S, Baral A.   +4 more
europepmc   +2 more sources

Somatostatin receptor expression in parathyroid neoplasms [PDF]

Endocrine Connections, 2019
Introduction Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging. The diagnostic criteria for parathyroid carcinoma are local and/or metastatic spreading.
Storvall, Sara, Leijon, Helena, Ryhänen, Eeva, Louhimo, Johanna, Haglund, Caj, Schalin-Jäntti, Camilla, Arola, Johanna   +6 more
openaire   +4 more sources

Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]

, 2014
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO, ERDAS, ENRICO, Medas F, NICOLOSI, ANGELO, Pisano G, Podda F, Santa Cruz R   +6 more
core   +1 more source

Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]

, 2013
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Bertherat, Jérôme, Beuschlein, Felix, Bonnet, Stéphane, Gaujoux, Sébastien, Guillaud-Bataille, Marine, Hantel, Constanze, Launay, Pierre, Lefèvre, Lucile, Perlemoine, Karine, Ragazzon, Bruno, Rizk-Rabin, Marthe, Tissier, Frédérique   +11 more
core   +7 more sources

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F., Dralle, H., Frank-Raue, K., Frilling, A., Haase, R., Hampel, R., Höppner, W., Kirchner, R., Klempa, J., Kotzerke, J., Mann, K., Raue, F., Rendl, J., Ritter, M. M., Scholz, G. H., Seif, F.   +15 more
core   +1 more source

Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery [PDF]

, 2016
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of intraoperative neuromonitoring (IONM) versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults ...
Abraha, Iosief, Arezzo, Alberto, Avenia, Nicola, Barczyñski, Marcin, Cirocchi, Roberto, D'ANDREA, Vito, Passera, Roberto, Randolph, Justus   +7 more
core   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Genetic and Epigenetic Alterations in Parathyroid Neoplasms

Iranian Journal of Pathology, 2022
The exact etiology of parathyroid carcinomas (PC) is still unknown. Their associations have with several inherited syndromes or specific genetic lesions have been established. The management of PC is challenging for clinicians. The complexity of molecular phenotypes increases with tumor aggressiveness.
Miratashi Yazdi, Seyed Amir, Nazar, Elham   +1 more
openaire   +2 more sources