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Differentiating Atypical Parathyroid Neoplasm from Parathyroid Cancer
Annals of Surgical Oncology, 2016The differentiation of benign parathyroid gland atypia and true parathyroid carcinoma (PC) can be challenging. In some instances, patients are classified as having 'atypical parathyroid neoplasms' (APNs), explicitly acknowledging that the distinction between benign and malignant disease appears impossible to determine.
Michelle D. Williams +9 more
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Clinical course of atypical parathyroid neoplasm with soft tissue extension
Journal of Surgical OncologyAbstractBackground and ObjectivesThe American Joint Committee on Cancer (AJCC) TNM staging system defines atypical parathyroid neoplasia (APN) as tumor in situ (Tis) and reserves the definition of parathyroid carcinoma (PC) to parathyroid tumor with invasion into surrounding structures.
Hope A, Feldman +9 more
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International journal of scientific research, 2021
Ectopic parathyroid adenomas in thyroid tissue are uncommon (0.7 - 6%), and their oncocytic variants are exceedingly rare. We report two cases of intrathyroid parathyroid adenoma which were diagnosed as Hurthle cell adenoma on cytology.
M. Lahori, Hua Chen
semanticscholar +1 more source
Ectopic parathyroid adenomas in thyroid tissue are uncommon (0.7 - 6%), and their oncocytic variants are exceedingly rare. We report two cases of intrathyroid parathyroid adenoma which were diagnosed as Hurthle cell adenoma on cytology.
M. Lahori, Hua Chen
semanticscholar +1 more source
Spectrum of mitochondrial genomic variation in parathyroid neoplasms
Endocrine, 2021Mitochondrial DNA (mtDNA) variations have been implicated in various cancer types. Several attempts have been made in benign parathyroid adenoma (PA); however, mtDNA variants and copy number alterations have not been investigated in parathyroid carcinoma (PC).
Ya Hu +7 more
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Parathyroid Neuroendocrine Neoplasms
2020The parathyroid glands are the site of common benign neuroendocrine tumors, including adenomas and lipoadenomas. Metastatic disease is very rare, and local growth does not usually have significant sequelae; even large non-metastatic tumors are easily resected.
Sylvia L. Asa +4 more
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[Clinical analysis of parathyroid neoplasms].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2010目的 探讨甲状旁腺良性肿瘤的诊断及治疗经验.方法 回顾性分析6例甲状旁腺良性肿瘤患者的临床资料,其中女2例,男4例;年龄为36～62岁,中位年龄59岁.结果 6例甲状旁腺良性肿瘤中甲状旁腺腺瘤5例,甲状旁腺囊肿1例,4例伴有甲状旁腺功能亢进症状,6例患者血钙、血磷血甲状旁腺激素均升高.术前多普勒超声定位的诊断准确率为66.7%（4/6）,甲状旁腺显像定位诊断准确率为60%（3/5）.6例患者均行肿瘤切除和（或）探查术,均获得临床治愈.随访时间5个月至3年,中位随访时间2年.结论 临床医师应对高度怀疑甲状旁腺疾病的患者进行血钙、血磷、血甲状旁腺激素检测.术前影像学检查应首选多普勒超声,并辅以甲状旁腺显像检查.手术切除是最佳的治疗手段.
Xiu-mei Chen, Qing-quan Zhang
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Epigenetic processes in sporadic parathyroid neoplasms
Molecular and Cellular Endocrinology, 2018Parathyroid tumors (PTs) are highly variable in their genetic background. Increasing evidence demonstrates that endocrine diseases can be caused by epigenetic alterations. The present review is focused on epigenetic aberrations related to PTs. DNA methylation, posttranslational histone modification, and noncoding RNAs are epigenetic mechanisms involved
Angelica M. Silva-Figueroa +1 more
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Advances in Anatomic Pathology, 2022
The diagnosis of “follicular neoplasm” (FN) in thyroid cytopathology has a long history that originated not long after the practice of fine-needle aspiration (FNA) of thyroid nodules.
N. Ohori, Michiya Nishino
semanticscholar +1 more source
The diagnosis of “follicular neoplasm” (FN) in thyroid cytopathology has a long history that originated not long after the practice of fine-needle aspiration (FNA) of thyroid nodules.
N. Ohori, Michiya Nishino
semanticscholar +1 more source