Results 81 to 90 of about 25,264 (186)

Glycomic profiling of parathyroid neoplasms via lectin microarray analysis

Endocrine
Parathyroid carcinoma (PC) is a rare malignancy with a poor prognosis. Diagnosis of PC is often difficult in clinical practice and efficient diagnostic markers are still needed for differential diagnosis. Aberrant glycosylations of glycoproteins were identified with lectin microarray in various cancers, while relevant information is lacking in PC.In ...
Zheng, Qingyuan, Cui, Ming, Xiao, Jinheng, Yang, Sen, Chen, Tianqi, Shi, Yanan, Hu, Ya, Liao, Quan   +7 more
openaire   +2 more sources

Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta‐Analysis

Aging Cell, Volume 25, Issue 2, February 2026.
This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy, Yveline Malrechauffé, Emma Boretti, Sophie Van Heden, Dolores Sanchez‐Rodriguez, Yoke Mun Chan, Etienne Cavalier, Aurélie Ladang, Jean‐Yves Reginster, Jonathan Douxfils, Charlotte Beaudart   +10 more
wiley   +1 more source

Stromal Defense Against Cancer: An Unprecedented Mechanism Limiting Cancer Invasion Into the Bone

Cancer Science, Volume 117, Issue 2, Page 308-315, February 2026.
The roles of nonimmune systems in tumor regulation remain largely undefined. This article introduces a new concept, “stromal defense against cancer (SDAC),” which is based on recent findings that the periosteum actively responds to tumor proximity and physically impedes tumor invasion into bone.
Masayuki Tsukasaki, Hiroshi Takayanagi
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Clinical and genetic characteristics of Multiple Endocrine Neoplasia type 1 (MEN 1) syndrome in a small cohort of Swiss patients [PDF]

, 2015
Multiple endocrine neoplasia type 1 (MEN1) syndrome is a polyglandular autosomal dominant transmitted disease characterized by the combined occurrence of several endocrine gland tumors.
ROSSIER, S.
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Synergistic associations of metformin and GLP‐1 receptor agonist use with adiposity‐related cancer incidence in people living with type 2 diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 946-959, February 2026.
Abstract Background Metformin and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) may reduce the risk of adiposity‐related cancers in patients with type 2 diabetes (T2D). The potential synergistic effects of these treatments on cancer incidence remain unclear, considering their distinct biological mechanisms and their associated effects on body ...
Alex E. Henney, Megan Heague, David R. Riley, Theresa J. Hydes, Matthew Anson, Uazman Alam, Daniel J. Cuthbertson   +6 more
wiley   +1 more source

Accuracy of Fine Needle Aspiration Biopsy with and without the Use of Tumor Markers in Cytologically Indeterminate Thyroid Lesions [PDF]

, 2010
We investigated if the use of two tumor markers, galectin-3 and CD44v6, could improve diagnostic accuracy of thyroid fine needle aspiration biopsy (FNAB) in cytologically indeterminate lesions (CIL).
Ivan Šamija, Neven Mateša, Zvonko Kusić   +2 more
core   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay, Sajin Marcus Cyr, Yorihiro Iwasaki, Elizabeth Hill, Eugene P. Rhee, Nevil J. Singh, Petra Simic, Murat Bastepe   +7 more
wiley   +1 more source

Interpretation of needle biopsies of the kidney for investigation of renal masses [PDF]

, 2018
The development of new therapeutic options for renal tumors has lead to the need of a pretherapeutic diagnosis for an increasing proportion of patients presenting with a renal mass. This need is particularly important for a small, incidentally discovered
de Leval, Laurence, Lhermitte, Benoît
core  

Genetic Characteristics of Pheochromocytomas: An Analysis of p16 Tumor Suppressor Gene Inactivation [PDF]

, 2006
Pheochromocytoma is a rare neuroendocrine tumor histologically characterized by chromaffin tissue and is comprised of catecholamine-containing neurosecretory granules.
Brewer, Alexander
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