Results 201 to 210 of about 420,147 (288)

Parental Stress and Caregiver Role Modulate Child–Caregiver Prosodic Synchrony in Autism: A Computational Analysis

open access: yesAutism Research, EarlyView.
ABSTRACT Parental stress influences parent–child interactions in typical development and is a prognostic factor of autism outcome. However, we still do not know to what extent parental stress affects parent–child interactions and whether caregiver role matters.
Maria Grazia Logrieco   +11 more
wiley   +1 more source

Remotely Delivering Real-Time Parent Training to the Home: An Initial Randomized Trial of Internet-Delivered Parent–Child Interaction Therapy (I-PCIT)

open access: yesJournal of Consulting and Clinical Psychology, 2017
Jonathan S. Comer   +15 more
semanticscholar   +1 more source

Urban–Rural Differences and Sex‐Specific Cognitive Effects on Autism Symptom Trajectories: A Longitudinal Study of Autistic Children in Taiwan

open access: yesAutism Research, EarlyView.
ABSTRACT Few longitudinal studies have mapped autism symptom trajectories outside Western contexts. This study aimed to characterize trajectories of autism symptoms, assessed using the Autism Diagnostic Observation Schedule (ADOS), and associated child and family factors among autistic children from two regions in Taiwan that differ by urbanicity ...
Yun‐Ju Chen   +8 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng   +4 more
wiley   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon   +13 more
wiley   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen   +4 more
wiley   +1 more source

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