Results 51 to 60 of about 420,147 (288)

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

A Different Approach to Mother and Child Interaction: Theraplay Play Therapy [PDF]

Psikiyatride Güncel Yaklaşımlar
Theraplay is an interaction and attachment based play therapy model which aims to increase self-esteem and confidence. It is also an approach that aims to lead healthy parent and child relationships with secure attachment and improvement in current ...
Arzu Akar Gencer, Ayse Belgin Aksoy
doaj   +1 more source

Stage 1 Registered Report: The experiences and perceptions of parent-child interaction therapy for parents of young children with communication difficulties: A qualitative evidence synthesis protocol [version 2; peer review: 2 approved]

HRB Open Research, 2020
Background: Parent-child interaction therapy refers to a group of interventions mediated by trained parents to address areas of developmental difficulties in children.
Ciara O'Toole, Rena Lyons, Donna Ó’Doibhlín, Fia O’Farrell, Catherine Houghton   +4 more
doaj   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Systematic review of interventions for the secondary prevention and treatment of emotional abuse of children by primary carers [PDF]

, 2008
Background Emotional abuse (or psychological maltreatment, as it is more commonly called in the US) is an inadequately researched and poorly understood concept, despite increasing awareness about the harm it can cause to children‟s lives.
Barlow, Jane, Carter, Yvonne, McMillan, Anita Schrader, Paul, Moli, Sidebotham, Peter, Stewart-Brown, Sarah L.   +5 more
core  

Treatment Outcomes for Toddlers with Behaviour Problems from Families in Poverty [PDF]

, 2009
Background. Relatively few treatment studies address mental health issues in very young children. This study examined the effectiveness of a treatment program for toddlers whose behavior problems were further complicated by living in poverty. Method.
American Psychiatric Association, Bagner, Baker, Baker, Behan, Brenner, Campbell, Campbell, Crawley, Einfeld, Eyberg, Eyberg, Eyberg, Feldman, Fox, Fox, Fox, Fox, Gavidia-Payne, Greene, Hofstra, Holtz, Huaqing Qi, Kaufman, McIntyre, Mendez, Nicholson, Nicholson, Nix, Nock, Patterson, Reid, Roberts, Roberts, Sanders, Sigafoos, Snell-Johns, US Department of Education, Webster-Stratton, Weis   +39 more
core   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

One-year follow-up of family versus child CBT for anxiety disorders: Exploring the roles of child age and parental intrusiveness. [PDF]

, 2009
ObjectiveTo compare the relative long-term benefit of family-focused cognitive behavioral therapy (FCBT) and child-focused cognitive behavioral therapy (CCBT) for child anxiety disorders at a 1-year follow-up.MethodThirty-five children (6-13 years old ...
McLeod, Bryce D, Piacentini, John C, Sigman, Marian, Wood, Jeffrey J   +3 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source