Results 111 to 120 of about 2,189,507 (275)

Past domestic helper-child and parent-child and attachment as predictors of adult attachment

, 2020
Many families in Hong Kong hire domestic helpers to elevate child care stress; however, limited is known regarding how such a unique phenomenon may influence the children’s later development. This study aimed to investigate whether past domestic helper-child attachment predicts adult attachment and romantic relationship satisfaction.
openaire   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Sibling relationships as a mediator and a moderator between parental attachment and depression among adolescents

BMC Psychology
Depression threatens adolescents’ psychological health and is influenced by negative interpersonal relationships. Previous studies have explored the effect of a negative parent−child relationship on adolescent depression but have ignored the frequent ...
Beibei Kuang, Yujing Zhao, Baojing Zhang, Jue Deng, Huahua Hu, Tong Ge   +5 more
doaj   +1 more source

Infant-mother attachment security, contextual risk, and early development: A moderational analysis [PDF]

, 2002
In light of evidence that the effects of attachment security on subsequent development may be contingent on the social context in which the child continues to develop, we examined the effect of attachment security at age 15 months, cumulative contextual ...
Fearon, RMP, Belsky, J
core  

A Breadth‐First Pruned‐Enriched Rosenbluth Method for Force–Extension Simulations of Confined Semiflexible Chains

Advanced Intelligent Discovery, EarlyView.
The behaviors of semiflexible polymers such as DNA and protein are often reshaped by coupled interactions. Monte Carlo simulations assist in studying these systems. This work recasts the traditional chain‐growth strategy into a new framework: a fixed number of chains grow synchronously, while less relevant chains to the target system are removed and ...
Yihan Zhao, Jizeng Wang
wiley   +1 more source

Pre‐Curved Everting Robots With Embedded Steering Intelligence Fabricated by CO2 Laser Welding

Advanced Intelligent Systems, EarlyView.
Design and experimental demonstration of a laser welded growing robot for anatomically guided navigation. The robot follows an aortic arch phantom entering the branchiocephalic branch through steering by design. The figure shows the physical phantom setup, CAD defined weld geometry and full robot eversion.
Brandon Saldarriaga, Panagiotis Kalozoumis, Panagiotis Vartholomeos, Carlo Seneci, Kawal Rhode, Christos Bergeles   +5 more
wiley   +1 more source

Parent-child attachment and executive functioning in relation to ADHD symptoms in middle childhood

, 2012
This study investigated attachment representations and executive functioning (i.e., response inhibition and working memory) at age 8 1/2 in relation to ADHD symptoms one year later.
Rydell, Ann-Margret,, Bohlin, Gunilla,, Thorell, Lisa B.   +2 more
core   +1 more source

AI‐Based Immortality: The Ethical Advantage of the Aretai Approach

AI &Innovation, EarlyView.
ABSTRACT The convergence of artificial intelligence, digital identity technologies, and biogerontological ambitions has produced a novel set of philosophical problems that have not yet been adequately addressed within mainstream bioethical discourse. Digital life extension—encompassing AI‐generated avatars, neural data preservation, mind uploading, and
Mirko Daniel Garasic
wiley   +1 more source

The Time of the Infant, Parent-Infant Desynchronization and Attachment Disorganization, or How Long Does it Take for a Preventive Action to be Effective? [PDF]

The classical version of early development by psychoanalysis has been largely challenged by developmental psychology, and particularly by attachment theory.
Antoine Guedeney, Romain Dugravier, Thomas Saias, Nicole Guedeney, CAPEDEP Study Group, Bertrand Welniarz, Susana Tereno, Tim Greacen   +7 more
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