Results 201 to 210 of about 2,189,507 (275)

A successful periodontal‐orthodontic treatment of an advanced case of dental trauma in a 9‐year‐old patient: A case report with 16‐year follow‐up

Clinical Advances in Periodontics, EarlyView.
Abstract Background Traumatic dental injury (TDI) most often requires complex and interdisciplinary management. Several factors are associated with the success of TDI treatment, including proper treatment planning and periodontal maintenance. Methods The present 16‐year follow‐up report describes the interdisciplinary management of an extrusive ...
João Carnio, Maísa Casarin, João Kreling Carnio, Flavia Q. Pirih   +3 more
wiley   +1 more source

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

Chemistry – A European Journal, EarlyView.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt, Henriette Hartung, Jonah Kammer, Norbert Sewald   +3 more
wiley   +1 more source

Peptide Marriages: Modular Assembly of Multi‐Agonist Therapeutics

Chemistry – A European Journal, EarlyView.
A modular polyethylene glycol (PEG) scaffold enables rapid assembly of dual peptide agonists using strain‐promoted azide–alkyne cycloaddition (SPAAC) and copper‐catalysed azide–alkyne cycloaddition (CuAAC). Glucagon‐like peptide‐1 (GLP‐1) and amylin agonists were combined with controlled valency, yielding low‐picomolar activity and receptor‐selective ...
Kristina A. Kostadinova, Jan L. Venne, Sona Krajcovicova, James Dodgson, Wouter F. J. Hogendorf, Thomas E. Nielsen, David Hymel, Hannah Bolt, Andie Collinson, Jason Day, Jefferson Revell, David R. Spring   +11 more
wiley   +1 more source

Charge Resonance Interaction in Aromatic Trimer Radical Cations Revealed by IR Spectroscopy: The Case of Pyrrole Homo‐ and Heterotrimers

Chemistry – A European Journal, EarlyView.
We demonstrate the power of high‐resolution infrared spectroscopy and complementary quantum chemical calculations to unravel the evolution of the aromatic charge resonance interaction (CR) in cold trimer radical cations for the prototypical pyrrole clusters.
Dashjargal Arildii, Otto Dopfer
wiley   +1 more source

Silica‐Supported Mononuclear Methyl‐Platinum Complexes Stabilized by Trimethylphosphine—Synthesis, Structure, and Reactions Under Reducing Conditions

Chemistry – A European Journal, EarlyView.
The article describes the synthesis and molecular transformations of a silica‐supported bis(phosphine)methylplatinum(II) complex under reactive (H2, CO) and inert gas atmospheres. The focus lies on the stabilizing effect of the sterically non‐demanding trimethylphosphine ligand, which alters the reactivity of the surface sites, compared to other ...
Lea S. Kopietz, Sven Schaefer, Oksana Storcheva, Gabriele Raudaschl‐Sieber, Johannes Bitzer, Wolfgang Kleist, Klaus Köhler   +6 more
wiley   +1 more source

Cyclization of a 1,8‐Diphenylanthracene by Scholl Reactions to Form Five‐ and Seven‐Membered Ring Embedded Polycyclic Aromatic Hydrocarbons

Chemistry – A European Journal, EarlyView.
Reactions of 10‐mesityl‐1,8‐diphenylanthracene with DDQ/TfOH produced three products via sequential formation of a five‐ or seven‐membered ring. Unexpectedly, the triply cyclized product with a rubicene substructure was formed through cyclization involving 1,2‐methyl shift.
Tatsuhiro Sasaki, Eiji Tsurumaki, Shinji Toyota   +2 more
wiley   +1 more source

Isolable ArInH2: Double Hydroindation Agent

Chemistry – A European Journal, EarlyView.
Stable crystalline monomeric indium dihydride ArInH2 was isolated and completely characterized using effective support of the P,C,P‐pincer ligand (Ar = 2,6‐(tBu2PO)2C6H3). It serves as unparalleled hydroindation agent, thereby extending the family of known hydrometallation process relying on heavy p‐block metals.
Adam Hochmal, Zdeňka Růžičková, Aleš Růžička, Roman Jambor, Milan Erben, Libor Dostál   +5 more
wiley   +1 more source

Halogenated Tryptophans Improve Integrin αVβ6 Affinity of Cyclic RGD Peptides and Provide Handles for Late‐Stage Derivatization

Chemistry – A European Journal, EarlyView.
Lighting up αVβ6: Halotryptophan engineering converts an RGD scaffold into a modular αVβ6 ligand platform, enabling picomolar affinity and late‐stage functionalization. The resulting probes combine high selectivity with fluorescence for FACS and tumor imaging.
Beate Nachtigall, Caroline Brinkmann, Jana Langosch, Anke Nieß, Norbert Sewald   +4 more
wiley   +1 more source