Results 131 to 140 of about 630,730 (284)
Early Social Interaction: A Case Comparison of Developmental Pragmatics and Psychoanalytic Theory [PDF]
, 2014 This book brings together various threads of the research work I have been involved with over a number of years. This research is based on a longitudinal video recorded study of one ofmydaughters as shewas learning howto talk. The impetus for engaging
Forrester, Michael A.
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Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
Advanced Science, EarlyView.This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Advanced Science, EarlyView.A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li +7 more
wiley +1 more source
Tindakan Orangtua dalam Menyekolahkan Anak Berkebutuhan Khusus pada Layanan Pendidikan Inklusif di Sekolah Dasar Negeri 1 Tanjung Kecamatan Purwokerto Selatan Kota Purwokerto [PDF]
, 2015 Education is the right for every Indonesian citizens, include the education for children with special needs (disability). Every parents who has child like this has aproblem in looking for special schools in order to give a good education for ...
Haryono, B. (Bagus) +2 more
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Nanoscale Mapping of the Subcellular Glycosylation Landscape
Advanced Science, EarlyView.Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter +4 more
wiley +1 more source
Parent Interaction Between an Infant with a Cochlear Implant and Additional Disabilities [PDF]
, 2019 Pediatric hearing loss has many spoken language learning issues that can impact parent-infant interaction. Moreover, additional disabilities are likely to increase stress, which could have cascading effects on communication.
Southern, Lillian
core +1 more source
Advanced Science, EarlyView.This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
The third voice: Do enhanced e-books enhance the benefits of shared story reading with preschoolers? [PDF]
, 2016 This study from which this paper draws examined the benefits of reading plain e-books (with parental instruction) compared to enhanced e-books (with limited parental direction) with 3- to 5-year-old children. Interaction was measured through parent-child
Ciffone, Katie +2 more
core +1 more source
Advanced Science, EarlyView.Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source