Results 41 to 50 of about 630,730 (284)

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Cooperation and conflict in family decision making [PDF]

open access: yes, 2008
This study addresses the family dynamics of the decision making process, in particular the issues of cooperation and conflict, in both two parent and lone parent families.
Catterall, M., Hamilton, K.L.
core  

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Developing and evaluating a lay health worker delivered implementation intervention to decrease engagement disparities in behavioural parent training: a mixed methods study protocol. [PDF]

open access: yes, 2019
IntroductionBehavioural parent training (BPT) programmes are effective in preventing and treating early-onset conduct problems and child maltreatment. Unfortunately, pervasive mental health service disparities continue to limit access to and engagement ...
Barnett, Miya   +5 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

The effectiveness of the parent-child interaction intervention program based on emotion coaching on the symptoms of children\'s separation anxiety disorder

open access: yesمجله علوم روانشناختی, 2021
Background: Numerous studies have been conducted on the effectiveness of the parent-child interaction intervention program and the symptoms of separation anxiety disorder in children.
Masoomeh Takhti   +3 more
doaj  

The specificity, situational modulations, and behavioral correlates of parent-child neural synchrony

open access: yesFrontiers in Human Neuroscience, 2022
In recent years, aiming to uncover the neural mechanism of parent-child interaction and link it to the children’s social development, a newly developed index, namely, parent-child inter-brain neural synchronization (INS) has attracted growing interest ...
Yi Liu, Jiaxin Li, Qi Wang, Yarong Li
doaj   +1 more source

Faktor-Faktor Keluarga dan Tingkah Laku Penyalahgunaan Dadah: Satu Kajian Perbandingan antara Penyalahguna Dadah dengan Bukan Penyalahguna Dadah [PDF]

open access: yes, 1993
The present study compares aspects of parent-child communication, parent-child nurturance, and family members involvement in drug abuse between drug abusers and non-drug abusers.
Al Hadi, H. M. Abdullah
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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