Results 51 to 60 of about 230,967 (299)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Childhood loneliness as a predictor of adolescent depressive symptoms: an 8-year longitudinal study [PDF]

, 2009
Childhood loneliness is characterised by children’s perceived dissatisfaction with aspects of their social relationships. This 8-year prospective study investigates whether loneliness in childhood predicts depressive symptoms in adolescence, controlling ...
A Gerson, A Henin, A Marcoen, AM Sund, B Birmaher, BG Tabachnick, BM Hagerty, C Connors, DCR Kerr, DM Ferguson, DM Ferguson, DW Nangle, E Cowen, E Fombonne, ES Buhs, GW Ladd, J Adams, J Cohen, J Flora, J Kistner, JB Kupersmidt, JD Coie, JE Dumas, JE Young, JH Valery, JL Borelli, JL Luby, JM Martin, JT Cacioppo, JT Cacioppo, KD Rudolph, Ken J. Rotenberg, KJ Rotenberg, L Goossens, L Murry, LA Peplau, LC Hawkley, LD Leve, LJ Koenig, LJ Koenig, LL Carstensen, LS Aiken, LY Abramson, M Boivin, M Brendgen, M Kovacs, M Rutter, MJ Prinstein, NK Eberhart, P Qualter, P Qualter, P Qualter, Pamela Qualter, PD Renshaw, Penny Munn, R Heikkinen, RP Lorion, RP Weissberg, S Harter, S Hymel, S Lau, S Nolen-Hoesksema, S Pederson, Stephen L. Brown, WF Panak, WT Boyce   +65 more
core   +5 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Parent–Child Interaction Therapy: current perspectives

Psychology Research and Behavior Management, 2017
Corey C Lieneman, Laurel A Brabson, April Highlander, Nancy M Wallace, Cheryl B McNeil Department of Psychology, West Virginia University, Morgantown, WV, USA Abstract: Parent–Child Interaction Therapy (PCIT) is an empirically ...
Lieneman CC, Brabson LA, Highlander A, Wallace NM, McNeil CB   +4 more
doaj  

Occupational Therapy’s Role in Early Language Development of Babies and Young Children [PDF]

, 2018
Occupational therapy practitioners in their interactions with babies, young children and their families, can be change-agents who promote rich language environments as a foundation to social interactions, social participation and academic successes. OTPs
Ketchum, OTD, OTR/L, Aimee E., Potvin, PhD, OTR/L, Marie-Christine   +1 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Effects of Mozart–Orff parent–child music therapy among mothers and their preschool children with autism spectrum disorder: A mixed-methods randomised controlled trial

BMC Pediatrics
Background Autism spectrum disorder (ASD) negatively impacts mental health, particularly in mothers of autistic children who experience heightened stress.
Yingshuang He, Arkers Wong, Yuhong Zhang, Jinling Lin, Hao Li, Bingyue Zhao, Tingting Chen, Shuixiu Huang, Rongfang Hu, Guihua Liu   +9 more
doaj   +1 more source

Parent–child interaction in motor speech therapy

Disability and Rehabilitation, 2016
Purpose: This study measures the reliability and sensitivity of a modified Parent–Child Interaction Observation scale (PCIOs) used to monitor the quality of parent–child interaction. The scale is part of a home-training program employed with direct motor speech intervention for children with speech sound disorders.
Aravind Kumar, Namasivayam, Vibhuti, Jethava, Margit, Pukonen, Anna, Huynh, Debra, Goshulak, Robert, Kroll, Pascal, van Lieshout   +6 more
openaire   +2 more sources

Evaluation of a University-Community Partnership to Provide Home-Based, Mental Health Services for Children from Families Living in Poverty [PDF]

, 2013
A university-community partnership is described that resulted in the development of community-based mental health services for young children from families living in poverty.
Fox, Robert A., Gresl, Brittany L., Mattek, Ryan   +2 more
core   +1 more source

A new parenting-based group intervention for young anxious children: results of a randomized controlled trial [PDF]

, 2011
Objective Despite recent advances, there are still no interventions that have been developed for the specific treatment of young children who have anxiety disorders.
Cartwright-Hatton, Sam, Dixon, Clare, Field, Andy P, Gallagher, Bridie, Harrington, Richard, Laskey, Ben, McNally, Deb, Miller, Chloe, Pemberton, Kathryn, Rust, Stewart, Symes, Wendy, White, Caroline, Woodham, Adrine   +12 more
core   +1 more source