Results 191 to 200 of about 7,561,238 (288)

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

open access: yesAdvanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang   +15 more
wiley   +1 more source

Toward relationship-based child welfare services

open access: yes
A relationship-based theoretical framework for child welfare services is proposed. Research literature is reviewed relative to attachment theory, relationship quality of maltreated child-parent and maltreated child-surrogate parent dyads, and effective ...
Goodman, Gail S.   +2 more
core  

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Multicomponent Molecular Editing of Polybutadiene: From Design Space to Battery Function

open access: yesAdvanced Science, EarlyView.
Multicomponent molecular editing transforms polybutadiene into an 18‐member polymer library with tunable thermal properties, nanoscale organization, and molecular dynamics. Mapping this multidimensional design space reveals distinct molecular input–property relationships and guides the selection of a candidate electrolyte additive for lithium–sulfur ...
Janna Jeschke   +8 more
wiley   +1 more source

Steric‐Pressure‐Driven Topological Reconstruction for High‐Performance Zintl Phase Thermoelectrics with Machine‐Learning Validation

open access: yesAdvanced Science, EarlyView.
Synergistic Sr and Ag co‐doping drives steric‐pressure‐induced reconstruction from a 2D layered structure to a cross‐linked 3D framework in the Ca9‐xSrxZn4+y‐zAgzSb9 system, enhancing carrier mobility while maintaining a large Seebeck coefficient and doubling ZT to 0.73 at 873 K, with hybrid transfer machine learning further capturing the compositional
Siyeon Kim   +7 more
wiley   +1 more source

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