Results 51 to 60 of about 931,494 (296)

HUBUNGAN ANTARA KUALITAS INTERAKSI ORANG TUA-ANAK DALAM KELUARGA DENGAN KECENDERUNGAN JUVENILE DELINQUENCY [PDF]

open access: yes, 2006
Trends Juvenile delinquency is a desire to commit acts contrary to law, religion, and the norms of society, so the result can be harming themselves, harming others and disturb the peace committed by juveniles in the form of group or individual.
Setyaningrum, Galuh Tri Wahyuningsih
core  

Continuing bonds with the living : bereaved parents’ narratives of their emotional relationship with their children [PDF]

open access: yes, 2017
© 2017 Cruse Bereavement Care.The death of a child can be seen as one of the most devastating experiences for parents which can result in a unique and enduring grief.
Nolte, Lizette   +2 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Demographic Changes and Parent–Child Relationships [PDF]

open access: yesParenting, 2006
This tutorial describes demographic changes and their implications for parenting and parent–child relationships. First, we discuss 2 major sociodemographic changes—declining fertility and increasing longevity—from the point of view of social demography.
Trommsdorff, Gisela, Nauck, Bernhard
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Parent-Child Relationships and Mindfulness

open access: yesNippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 2012
Psychological approaches such as mindfulness-based stress reduction or mindfulness-based cognitive therapy could be effective for relieving a wide range of psychosocial stresses or frictions between parents and children. Several interventional approaches based on mindfulness have been shown to be useful for improving parent-child relationships not only
Kouichi, Yoshimasu   +4 more
openaire   +3 more sources

Parent-Child Closeness and Coping Outcomes in Emerging Adulthood [PDF]

open access: yes, 2017
Parents continue to play a pivotal role in their children’s social and emotional adjustment into emerging adulthood (Mounts et al., 2006). This project examined the effect of parent-emerging adult closeness on emerging adult coping responses, and whether
Stormberg, Rebecca Lee
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

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