HUBUNGAN ANTARA KUALITAS INTERAKSI ORANG TUA-ANAK DALAM KELUARGA DENGAN KECENDERUNGAN JUVENILE DELINQUENCY [PDF]
Trends Juvenile delinquency is a desire to commit acts contrary to law, religion, and the norms of society, so the result can be harming themselves, harming others and disturb the peace committed by juveniles in the form of group or individual.
Setyaningrum, Galuh Tri Wahyuningsih
core
Continuing bonds with the living : bereaved parents’ narratives of their emotional relationship with their children [PDF]
© 2017 Cruse Bereavement Care.The death of a child can be seen as one of the most devastating experiences for parents which can result in a unique and enduring grief.
Nolte, Lizette +2 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Demographic Changes and Parent–Child Relationships [PDF]
This tutorial describes demographic changes and their implications for parenting and parent–child relationships. First, we discuss 2 major sociodemographic changes—declining fertility and increasing longevity—from the point of view of social demography.
Trommsdorff, Gisela, Nauck, Bernhard
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Parent-Child Relationships and Mindfulness
Psychological approaches such as mindfulness-based stress reduction or mindfulness-based cognitive therapy could be effective for relieving a wide range of psychosocial stresses or frictions between parents and children. Several interventional approaches based on mindfulness have been shown to be useful for improving parent-child relationships not only
Kouichi, Yoshimasu +4 more
openaire +3 more sources
Parent-Child Closeness and Coping Outcomes in Emerging Adulthood [PDF]
Parents continue to play a pivotal role in their children’s social and emotional adjustment into emerging adulthood (Mounts et al., 2006). This project examined the effect of parent-emerging adult closeness on emerging adult coping responses, and whether
Stormberg, Rebecca Lee
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source

