Results 181 to 190 of about 5,583,023 (318)

Everyday Discrimination in Young Adulthood and Depressive Symptoms at Early Midlife: The Moderating Role of Parent-Child Relationships. [PDF]

Int J Environ Res Public Health
Herath B, Zhang X.
europepmc   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Parent psychological distress and parent-child relationships two years into the COVID-19 pandemic: Results from a Canadian cross-sectional study. [PDF]

PLoS One, 2023
Thomson KC, Jenkins E, Gill R, Hastings KG, Richardson CG, Gagné Petteni M, McAuliffe C, Gadermann AM.   +7 more
europepmc   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Problematic media use in early childhood: The role of parent-child relationships and parental wellbeing in families in New Zealand and the United States. [PDF]

J Child Media, 2023
Swit CS, Coyne SM, Shawcroft J, Gath M, Barr R, Holmgren HG, Stockdale L.   +6 more
europepmc   +1 more source

Machine Learning Potential for Calcium Silicate Hydrates With Broad Compositional and Structural Diversity

Advanced Science, EarlyView.
Existing machine learning potentials remain limited in their ability to generalize across the broad chemical and structural variability of C–S–H. Here, a representative DFT‐labeled dataset is constructed through large‐scale model generation, redundancy‐controlled screening, first‐principles optimization, and targeted sampling of non‐equilibrium ...
Yunjian Li, Cheng Chen, Roland J.‐M. Pellenq, Zongjin Li, Jiaping Liu   +4 more
wiley   +1 more source

Harsh parenting and preschool children's screen time: the mediating role of parent-child relationships and the moderating effect of mindful parenting. [PDF]

Front Psychol
Zhang C.
europepmc   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Identifying Areas to Improve Care and Support Parent-Child Relationships From the Perspective of Pregnant and Parenting People in Recovery. [PDF]

J Addict Med
Karnosh C, Simon J, Krans EE, Guyon-Harris KL.   +3 more
europepmc   +1 more source

Solidarity and ambivalence in parent-child relationships

, 2007
In this dissertation, new challenges for intergenerational family relationship research were formulated and empirically investigated. Major socio-demographic and socio-cultural developments have induced changes in Western family life. These were changes in the structure of families and changes in the nature of intergenerational family ties.
openaire   +4 more sources