Results 61 to 70 of about 905,038 (348)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Parental Substance Use in New Hampshire: Who Cares for the Children? [PDF]

, 2018
In this brief, author Kristin Smith examines parental substance use and who cares for children when their parents cannot. It uses data from the New Hampshire Department of Health and Human Services’ Division for Children, Youth, and Families Results ...
Smith, Kristin
core   +1 more source

Sex-biased parental care and sexual size dimorphism in a provisioning arthropod [PDF]

, 2015
The diverse selection pressures driving the evolution of sexual size dimorphism (SSD) have long been debated. While the balance between fecundity selection and sexual selection has received much attention, explanations based on sex-specific ecology have ...
A Herrel, AJS Weaving, AJS Weaving, AJS Weaving, AK Chippendale, AV Hedrick, B Hurlbutt, CH Hicks, CR Pavey, DJ Fairbairn, DJ Fairbairn, DJ Fairbairn, E Paradis, E Petersson, E Ranta, EJ Temeles, FD Parker, FE Kurczewski, G Halffter, G Head, G Shreeves, Gavin Shreeves, GB Monteith, GP Baerends, H Dollfuss, H Weimerskirch, HE Evans, HE Evans, HE Evans, HE Hinton, J Field, J Field, J Field, J Field, J Field, J Field, J Hunt, J Tormos, JA Powell, JA Rosenheim, JA Rosenheim, James D. J. Gilbert, JC Costa, JDJ Gilbert, JDJ Gilbert, Jeremy Field, JF Berry, JH Marden, JJ Gilbert, JR Coelho, JR Lighton, K Ralls, KM O’Neill, KM O’Neill, M Andersson, M Blösch, M Goubault, Martyn Kennedy, ME Favila, MF O’Brien, MS Iglesias, O Krüger, O Lomholdt, P Lindenfors, P Myers, P Wheeler, PB Edwards, PR Stephens, R Lande, R Shine, R Tornberg, RC Castillo del, RC Stillwell, RF Preziosi, RM Bohart, RM Cox, S Nylin, SC Stearns, SD Gaimari, Selina Brace, ST Trumbo, TE Reimchen, TH Clutton-Brock, VL Kazenas, W Groot De, WU Blanckenhorn, WU Blanckenhorn, X Han   +87 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Integrating a sense of coherence into the neonatal environment [PDF]

, 2013
Background: Family centred care (FCC) is currently a valued philosophy within neonatal care; an approach that places the parents at the heart of all decision-making and engagement in the care of their infant.
Axelin, Anna, Dykes, Fiona Clare, Flacking, Renee, Moran, Victoria Louise, Thomson, Gill   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Nurses' perspectives on the impact of the COVID-19 pandemic on parental involvement in NICUs

International Journal of Africa Nursing Sciences
Background: Nurses are key healthcare professionals in service provision to infants and their families in neonatal intensive care units and are pivotal in observing parental involvement in their infant’s care.
Sthembiso Ncube, Jeannie van der Linde, Maria du Toit, Marien Alet Graham, Renata Eccles   +4 more
doaj   +1 more source

GPs’ strategies in exploring the preschool child’s wellbeing in the paediatric consultation [PDF]

, 2013
Background: Although General Practitioners (GPs) are uniquely placed to identify children with emotional, social, and behavioural problems, they succeed in identifying only a small number of them.
A Heikkinen, A Poulsen, AM Skovgaard, AR Miller, BF Crabtree, C Nova, D Cawthorpe, D Hall, DA Schön, DA Schön, E Christensen, J Gabe, K Lykke, K Lykke, K Lykke, K Sayal, K Tates, Kirsten Lykke, L Flachs, LA King, LS Wissow, M Zwaanswijk, MH Theunissen, O Walker, P Cahill, P Cahill, P Christensen, Pia Christensen, PS Byrne, S Michelsen, Susanne Reventlow, VM Klein, YH Carter   +32 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source