The evolution of negotiation strategies diversifies parental cooperation
Parental cooperation is not self-evident, as conflicts often arise over individual contributions. Evolutionary game theory suggests this conflict may be resolved through negotiation, where parents adjust their care level based on their partner’s ...
Jia Zheng +2 more
doaj +1 more source
Paediatric neuropsychological assessment: an analysis of parents' perspectives [PDF]
Purpose: Modern healthcare services are commonly based on shared models of care, in which a strong emphasis is placed upon the views of those in receipt of services.
Bennett, Emily +5 more
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Dynamical Adaptation of Parental Care
Two models are proposed to simulate population growth of species with mature stage and immature stage in which there are parental cares for immature. It is assumed that the protection of mature to their immature reduces mortality of immature at the cost of reduction of reproduction. Dynamical adaptation of parental care is incorporated into the models,
Takeuchi, Yasuhiro +3 more
openaire +3 more sources
Neural Control of Maternal and Paternal Behaviors [PDF]
Parental care, including feeding and protection of young, is essential for the survival as well as mental and physical well-being of the offspring. A large variety of parental behaviors has been described across species and sexes, raising fascinating ...
Dulac, Catherine +2 more
core +1 more source
Associations of Parental Cancer With School Absenteeism, Medical Care Unaffordability, Health Care Use, and Mental Health Among Children [PDF]
Zhiyuan Zheng +5 more
openalex +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
The Impact of the Los Angeles Healthy Kids Program on Access to Care, Use of Services, and Health Status [PDF]
Presents survey results on the impact of the Healthy Kids program, which provides uninsured children with comprehensive coverage, on access to care, unmet needs, use of specialty and dental services, health status, and parental ...
Embry Howell, Lisa Dubay, Louise Palmer
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source

