Results 121 to 130 of about 2,108,472 (235)

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Migration-Related Characteristics and Children’s Consumption of Ultra-Processed Foods

open access: yesFoods
Ultra-processed foods (UPFs) have become a dominant component of contemporary food environments worldwide. Their consumption is socially patterned, with higher intakes frequently observed among children from socioeconomically disadvantage families ...
Josep A. Tur   +2 more
doaj   +1 more source

Which migration, what development. Unsettling the edifice of migration and development [PDF]

open access: yes, 2007
Raghuram P. Which migration, what development. Unsettling the edifice of migration and development. COMCAD Arbeitspapiere - working papers, 28.
Raghuram, Parvati
core  

Minimal Transport Units Govern Oxygen‐Defect Stabilization and Transport for Lightweight Solid Electrolytes

open access: yesAdvanced Science, EarlyView.
Lightweight borate chemistry combined with minimal transport units provides a new pathway for designing lightweight oxide‐ion solid electrolytes. ABSTRACT Solid electrolytes are central to electrochemical energy technologies, including fuel cells, sensors, catalysis, membrane separation, and electrolyser.
Xiaohui Li   +13 more
wiley   +1 more source

The determinants of international migration: conceptualizing policy, origin and destination effects: DEMIG project paper no. 2 [PDF]

open access: yes, 2011
The effectiveness of migration policies has been widely contested in the face of their supposed failure to steer immigration and their hypothesized unintended, counter-productive effects.
de Haas, Hein
core  

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

open access: yesAdvanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang   +18 more
wiley   +1 more source

The role of internal and international relative deprivation in global migration: DEMIG project paper no. 5 [PDF]

open access: yes, 2011
This paper analyses the role of internal (within-country) and international (bilateral and global) relative deprivation and absolute deprivation in international migration.
Czaika, Mathias, de Haas, Hein
core  

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

open access: yesAdvanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu   +3 more
wiley   +1 more source

Effects of Parental Migration on Dental Caries of Six- to Eight-Year-Old Children Using Structural Equation Modeling. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Liu S   +3 more
europepmc   +1 more source

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