Results 41 to 50 of about 863,294 (293)
Indian Journal of Ophthalmology, 2011 The aim of the study was to know the response of the relatives attending the squint surgery of their ward. A trained secretary administered an eight item questionnaire by live / telephonic interview.
Mihir Kothari
doaj +1 more source
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]
, 2016 Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel +4 more
core +1 more source
Soil contamination evaluation by Enrichment Factor (EF) and Geoaccumulation Index (Igeo) [PDF]
, 2015 Heavy metals are natural constituents of soils and their concentration varies depending on parental materials. The soils were formed by. In the last years, the content of heavy metal in soils has increased due to human activities as: distribution of ...
BARBIERI, Maurizio +2 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Genetic research in a public-private research consortium: prospects for indirect use of Elige breeding germplasm in academic research [PDF]
The creation of a public¿private research partnership between plant breeding industry and academia can be beneficial for all parties involved. Academic partners benefit from the material contributions by industry and a practically relevant research focus,
Berloo, R., van +5 more
core +2 more sources
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI [PDF]
, 2017 Background: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the ...
De Schauwer, Catharina +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The time benefits of young adult home stayers in France and Italy: a new perspective on the transition to adulthood? [PDF]
, 2017 This article analyses how two co-residing generations contribute to the housework workload in Italy and France during the early 2000s. It studies the intergenerational exchange of time between young adults and their parents by indirectly comparing the ...
Mencarini, Letizia +3 more
core +2 more sources
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source