Results 81 to 90 of about 7,474,211 (311)
Frontiers in PsychologyIntroductionGuided by ecological systems theory, this study employs psychological network analysis to investigate how parental and peer support interact with children’s football participation and whether these ecological dynamics differ by gender ...
Xiancheng Zeng, Wei He, Zhigang Guo
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Parents' Economic Support of Young-Adult Children: Do Socioeconomic Circumstances Matter? [PDF]
This paper assesses how the economic support provided by parents to young adults as they complete their education and enter the labor market is related to the family's socioeconomic circumstances.
Cobb-Clark, Deborah A., Gorgens, Tue
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Inclusive education: the role of parents and the importance of pedagogical and psychological support
Frontiers in EducationThis study examines parents’ perceptions of inclusive education in Kazakhstan, with particular attention to parental role and the importance of pedagogical and psychological support in their children's school experiences.
Beibitgul Turganbayeva +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
, 2013 Shannon A Morrison, Carol J Dashiff, David E Vance School of Nursing, University of Alabama, Birmingham, AL, USA Abstract: Parental influence to promote autonomy and self-determination in their children as they grow up may also motivate them to exercise ...
Vance DE, Morrison SA, Dashiff CJ
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Income Contingent Loans for Paid Parental Leave [PDF]
In early 2008 the federal government instructed the Productivity Commission (PC) to enquire into the social and economic policy issue of paid parental leave (PPL).
Bruce Chapman, Tim Higgins
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The Mediatory Role of Maladaptive Schema Modes Between Parental Care and Non-Suicidal Self-Injury [PDF]
, 2013 Non-suicidal self-injury (NSSI) is being increasingly recognised as a behaviour of significant clinical importance. Yet, there remains uncertainty regarding the underlying mechanisms of NSSI.
Power, K +4 more
core +1 more source