Results 131 to 140 of about 15,597 (255)

Neuromelanin‐Sensitive MRI as a Marker of Clinical Severity and Disease Burden in Parkinson's Disease: A Systematic Review and Meta‐analysis

Movement Disorders, EarlyView.
Abstract The neuropathology of Parkinson's disease (PD) is characterized in part by the degeneration of catecholaminergic neurons, particularly dopaminergic neurons in the substantia nigra pars compacta (SNpc) and noradrenergic neurons in the locus coeruleus (LC), yet no validated in vivo biomarker quantifies this process.
Rayo Akande, Thomas Kustermann, Štefan Holiga, Judith Anzures‐Cabrera, Patrik Brundin, Gennaro Pagano   +5 more
wiley   +1 more source

Post-SABR early PSA density kinetics in androgen deprivation therapy-naïve patients: early landmark models for long-term biochemical recurrence-free survival. [PDF]

Clin Transl Radiat Oncol
Greco C, Vieira B, Pares O, Pimentel N, Louro V, Nunes B, Kociolek J, Simas M, Fuks Z.   +8 more
europepmc   +1 more source

Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques, João Pedro Stringhetta Rahal, Rafael da Cunha Gomes Ribeiro, Enzo Bogucheski Ribeiro Machado, Carlos Antonio Negrato   +4 more
wiley   +1 more source

Multiple cranial neuropathy secondary to tuberculous meningitis and intracranial tuberculoma in an adolescent [PDF]

Biomedica
Pabón D, Rojas CA, Barco C.
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Measles vaccination status and evidence of immunity among medical students in Catalonia (Spain), 2023-2025: a cross-sectional study. [PDF]

BMC Med Educ
Domínguez A, Soldevila N, Toledo D, Casas I, Aldea M, Prat A, Bartolomé R, Borràs E, Godoy P, Working Group on Vaccine Preventable Diseases in Medical Students.   +9 more
europepmc   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

[Response to Francisco Paumgartten's contributions to "Maria José Deane, in her own (and our) words", published in volume 32]. [PDF]

Hist Cienc Saude Manguinhos
Maciel LR, Borges RS.
europepmc   +1 more source

Expanding the Phenotypic Spectrum of PMPCB‐Related Disease: Long‐Term Survival with Childhood‐Onset Ataxia

Movement Disorders Clinical Practice, EarlyView.
Ioannis Livanos, Christina Votsi, Marios Tomazou, Hermione Ugolini, Henry Houlden, Menelaos Pipis, Eleni Zamba Papanicolaou, Kyproula Christodoulou   +7 more
wiley   +1 more source