Results 41 to 50 of about 90,283 (282)

Contrastive self-knowledge [PDF]

open access: yes, 2014
In this paper, I draw on a recent account of perceptual knowledge according to which knowledge is contrastive. I extend the contrastive account of perceptual knowledge to yield a contrastive account of self-knowledge.
Sawyer, Sarah
core   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

open access: yesAdvanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng   +7 more
wiley   +1 more source

Muscle Spasticity and Its Interaction with Myofascial System of Children with Central Paresis [PDF]

open access: yes, 2019
Traditionally, the problem of muscle spasticity was considered by experts as a kind of local problem associated with the inhibition or traumatisation of the central motor neuron in a certain part of its path.
Moga, N. (Nikolay)
core   +3 more sources

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona   +15 more
wiley   +1 more source

A Novel Bilateral Data Fusion Approach for EMG-Driven Deep Learning in Post-Stroke Paretic Gesture Recognition

open access: yesSensors
We introduce a hybrid deep learning model for recognizing hand gestures from electromyography (EMG) signals in subacute stroke patients: the one-dimensional convolutional long short-term memory neural network (CNN-LSTM). The proposed network was trained,
Alexey Anastasiev   +10 more
doaj   +1 more source

Health-Related Quality of Life Outcomes from Botulinum Toxin Treatment in Spasticity

open access: yesToxins, 2020
Objective: The effects of botulinum toxin injections (BoNT) on health-related quality of life along the complex spectrum of spasticity needs further characterization to guide practitioners in a real-life therapeutic environment.
Lorenzo Pietro Roncoroni   +11 more
doaj   +1 more source

Hypoglossal schwannoma masquerading as a carotid body tumor. [PDF]

open access: yes, 2012
Study Objective. To describe the clinical presentation, evaluation, and treatment of a hypoglossal schwannoma. Methods. We report an unusual case of a hypoglossal schwannoma presenting as a pulsatile level II neck mass at the bifurcation of the external ...
Abie H. Mendelsohn   +4 more
core   +1 more source

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao   +9 more
wiley   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

open access: yesAnnals of Neurology, EarlyView.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani   +12 more
wiley   +1 more source

Laryngeal paresis and paralysis (Review)

open access: yesСучасні медичні технології, 2019
Same questions about etiology and clinical symptomatic of vocal fold paresis/paralysis, e. g. iatrogenic/traumatic, associated with neoplasm or with infectious and systemic diseases in this review are present.
V. A. Kashirin, A. D. Gusakov
doaj   +1 more source

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