Results 121 to 130 of about 65,077 (195)

Pareto optimal fronts of kinetic proofreading

Pareto optimal fronts of kinetic proofreading
Biological processes such as DNA replication, RNA transcription, and protein translation operate with remarkable speed and accuracy in selecting the right substrate from pools of chemically identical molecules. This result is obtained by non-equilibrium reactions that dissipate chemical energy.
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Generative Multiobjective Bayesian Optimization with Scalable Batch Evaluations for Sample-Efficient De Novo Molecular Design. [PDF]

Ind Eng Chem Res
Muthyala MR, Sorourifar F, Tan T, Peng Y, Paulson JA.   +4 more
europepmc   +1 more source

The geometry of the Pareto front in biological phenotype space. [PDF]

Ecol Evol, 2013
Sheftel H, Shoval O, Mayo A, Alon U.
europepmc   +1 more source

A prescription-free, radiobiology-based framework for automated VMAT planning: A feasibility study in primary prostate cancer radiotherapy. [PDF]

Med Phys
Kuhn D, Spohn SKB, Zamboglou C, Grosu AL, Baltas D, Sachpazidis I.   +5 more
europepmc   +1 more source

Pareto optimality reveals an atlas of cellular archetypes. [PDF]

Proc Natl Acad Sci U S A
Crowley G, Alon U, Quake SR.
europepmc   +1 more source

Archived multi-objective simulated annealing transient electromagnetic inversion. [PDF]

Sci Rep
An Y, Fan T, Li P, Wang H, Liu Z, Zhao Z, Liu Q, Li G, Li B.   +8 more
europepmc   +1 more source

Application of the quality control circle model to reduce non-conforming surgical instrument packaging and hospital-acquired infection risk: a pilot study. [PDF]

Front Cell Infect Microbiol
Mai L, Shen X, Zeng C, Lin C, Huang X, Pan C.   +5 more
europepmc   +1 more source

Data mining historical Chinese medical recipe collections and nuclear receptor profiling identify plant fractions that modulate glucocorticoid receptor activity. [PDF]

Front Pharmacol
Prackwieser J, Houtman R, Kievits T, Melchers D, Guan H, Seifert G, Konietschke F, Lamottke K, Unschuld PU, Kirk N.   +9 more
europepmc   +1 more source

Chemically-informed active learning enables data-efficient multi-objective optimization of self-healing polyurethanes. [PDF]

Chem Sci
Liang K, Qi X, Xiao X, Wang L, Zhang J.
europepmc   +1 more source