Results 141 to 150 of about 159,025 (301)

Production, characterization and immobilization of protease produced by Periconia byssoides

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The present work sought to broaden the repertoire of proteolytic biocatalyst formulations by producing, purifying, characterizing, and identifying suitable immobilization carriers for an extracellular protease from the filamentous fungi Periconia byssoides.
Juliana Mota de Oliveira, Pedro Fernandes, Luís Fernando Pascholati Gusmão, Sandra Aparecida de Assis   +3 more
wiley   +1 more source

Simulating competition in the US bioeconomy to produce hard‐to‐electrify transportation fuels using limited biomass resources

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study presents a novel bioeconomy optimization framework, BiOpt, designed to address critical questions regarding the strategic use of limited US biomass resources for biofuel production. By integrating detailed techno‐economic analyses, life cycle assessments, and resource assessment data, BiOpt optimizes resource distributions across ...
Nicholas A. Carlson, Emily K. Newes, Kristen Lu, Eric C. D. Tan   +3 more
wiley   +1 more source

Considering spatiotemporal evolutionary information in dynamic multi‐objective optimisation

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Preserving population diversity and providing knowledge, which are two core tasks in the dynamic multi‐objective optimisation (DMO), are challenging since the sampling space is time‐ and space‐varying. Therefore, the spatiotemporal property of evolutionary information needs to be considered in the DMO.
Qinqin Fan, Min Jiang, Wentao Huang, Qingchao Jiang   +3 more
wiley   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan, Han‐Jung Kuo, Yu‐Chieh Lin, Yen‐An Lu, Wei‐Shou Hu, Qi Zhang   +5 more
wiley   +1 more source

COMPROMISE, OPTIMAL AND TRACTIONAL ACCOUNTS ON PARETO SET

Nauka ta progres transportu, 2010
The problem of optimum traction calculations is considered as a problem about optimum distribution of a resource. The dynamic programming solution is based on a step-by-step calculation of set of points of Pareto-optimum values of a criterion function ...
V. V. Lahuta
doaj  

Tariffs in an Economy with Incomplete Markets and Unemployment [PDF]

This paper examines the optimal labor contract in a small open economy with incomplete markets under international price uncertainty. The effect on employment, wages, and profits of different realizations of the state of nature is studied and agents ...
Raquel Fernandez
core  

Harnessing Generative AI for Sustainable Supply Chains: Lean, Circular and Green Perspectives

Business Strategy and the Environment, EarlyView.
ABSTRACT Generative artificial intelligence is playing a significant role in the transformation of digital ecosystems by reinventing the processes of content generation, process automation, product innovation and customer experience. At the same time that these technologies are becoming more integrated into routine operations, the focus has shifted to ...
Ashutosh Singh, Rsha Alghafes, Judit Petra Koltai, Sushant Kumar Vishnoi   +3 more
wiley   +1 more source

Simultaneous Maximization of Speed and Sensitivity in the Optimal Coordination of Directional Overcurrent Protections

Electricity
This paper presents the simultaneous maximization of speed and sensitivity in the Optimal Coordination of Directional Over-Current Protections (OC-DOCP), considering that maximum selectivity is maintained in all solutions.
Elmer Sorrentino
doaj   +1 more source

"Pareto Optimal Pro-cyclical Research and Development" [PDF]

We develop a perfectly competitive endogenous growth model in which R&D is the engine of growth. Our model generates pro-cyclical R&D investment and labor input as a pareto optimal response to technology shocks to the consumption and equipment good ...
R. Anton Braun, Tomoyuki Nakajima
core