Results 111 to 120 of about 255,392 (351)

Passive, yet not inactive: robotic exoskeleton walking increases cortical activation dependent on task

Journal of NeuroEngineering and Rehabilitation, 2020
Background Experimental designs using surrogate gait-like movements, such as in functional magnetic resonance imaging (MRI), cannot fully capture the cortical activation associated with overground gait.
Sue Peters, Shannon B. Lim, Dennis R. Louie, Chieh-ling Yang, Janice J. Eng   +4 more
doaj   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

Advanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang, Guofu Zhang, Yizhou Zhu, Jingcheng Wang, Xinmin Feng, Wenyong Fei, Jihang Dai, Le Hu, Yi Zhang, Jun Cai, Binjia Ruan, Yue Jin, Fanhao Wei, Gang Lu, Dongan Wang, Jason Pui Yin Cheung, Graham Ka Hon Shea, Hao Chen, Kelvin Wai Kwok Yeung, Lei Wang, Yongxiang Wang   +20 more
wiley   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Free choice activates a decision circuit between frontal and parietal cortex [PDF]

, 2008
We often face alternatives that we are free to choose between. Planning movements to select an alternative involves several areas in frontal and parietal cortex that are anatomically connected into long-range circuits.
A Gail, A Riehle, B Pesaran, B Pesaran, DM Halliday, DM Kreps, G Goldberg, H Scherberger, H Scherberger, J Rickert, JG Kerns, JI Gold, LP Sugrue, ML Platt, MT Schmolesky, ND Daw, P Cisek, P Cisek, P Fries, PB Johnson, PP Mitra, R Bogacz, R Quian Quiroga, R Romo, SL Bressler, SP Wise, T Yang, TJ Buschman, U Mitzdorf, VN Murthy   +29 more
core   +2 more sources

Training‐Free Regulation of Grasping by Intracortical Tactile Feedback Designed via S1‐M1 Communication

Advanced Science, EarlyView.
During object grasping in macaques, information flow between the primary sensory cortex (S1) and the primary motor cortex (M1) is modulated by tactile properties of the target. Intracortical micro‐stimulation in S1 reliably evokes M1 responses that resemble those naturally generated during grasping under specific tactile conditions.
Qi Zhang, Bing Liu, Zhemeng Wang, Jiayue Zhou, Xingyi Yang, Qian Zhou, Yuwei Zhao, Siwei Li, Jin Zhou, Changyong Wang   +9 more
wiley   +1 more source

The Correlative Analysis of Amplitude-temporal Characteristics of Evoked Potentials of Brain Cortex in Sportsmen [PDF]

, 2017
The article considers the correlative analysis of amplitude-temporal characteristics of evoked potentials of brain cortex in sportsmen of playing kinds of sport and athletes at perception and processing of significant information “What” and “Where” in ...
Poruchynska, T. (Tеtiana), Romaniuk, A. (Alona), Shevchuk, T. (Tеtiana), Usova, O. (Oksana), Zhuravlov, O. (Oleksandr)   +4 more
core   +2 more sources

Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top‐Down Middle Cingulate Amygdala Regulation and Brain‐Wide Fear Representations

Advanced Science, EarlyView.
This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu, Shuyue Xu, Zheng Zhang, Dan Liu, Ting Xu, Yuan Zhang, Feng Zhou, Xiaodong Zhang, Chunmei Lan, Junjie Wang, Lan Wang, Jingxian He, Keith M Kendrick, Bharat Biswal, Dezhong Yao, Zhen Liang, Weihua Zhao, Benjamin Becker   +17 more
wiley   +1 more source

Sylvian fissure and parietal anatomy in children with autism spectrum disorder [PDF]

, 2012
Autism spectrum disorder (ASD) is characterized by deficits in social functioning and language and communication, with restricted interests or stereotyped behaviors.
Foundas, Anne L., Knaus, Tracey A., Tager-Flusberg, Helen   +2 more
core   +3 more sources

Parietal conditioning enhances motor surround inhibition

Brain Stimulation, 2020
Background: Motor surround inhibition (mSI) is a phenomenon supportive for executing selective finger movements, wherein synergist muscles are selectively facilitated while surround muscles are inhibited.
Nivethida Thirugnanasambandam, Giorgio Leodori, Traian Popa, Panagiotis Kassavetis, Alexandra Mandel, Alexander Shaft, Jaron Kee, Sarung Kashyap, Gregg Khodorov, Mark Hallett   +9 more
doaj  

Cough is dangerous:Neural correlates of implicit body symptoms associations

Frontiers in Psychology, 2016
The negative interpretation of body sensations (e.g., as sign of a severe illness) is a crucial cognitive process in pathological health anxiety (HA). However, little is known about the nature and the degree of automaticity of this interpretation bias ...
Daniela eMier, Michael eWitthöft, Josef eBailer, Julia eOfer, Tobias eKerstner, Fred eRist, Carsten eDiener   +6 more
doaj   +1 more source