Results 121 to 130 of about 269,905 (355)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen   +8 more
wiley   +1 more source

Cough is dangerous:Neural correlates of implicit body symptoms associations

open access: yesFrontiers in Psychology, 2016
The negative interpretation of body sensations (e.g., as sign of a severe illness) is a crucial cognitive process in pathological health anxiety (HA). However, little is known about the nature and the degree of automaticity of this interpretation bias ...
Daniela eMier   +6 more
doaj   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

open access: yesAdvanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu   +7 more
wiley   +1 more source

AMYLOID PRECURSOR PROTEIN IMMUNOHISTOCHEMICAL CHANGES IN THE NEWBORN MICE FRONTAL AND PARIETAL CEREBRAL CORTICES AFFECTED BY PRENATAL EXPOSURE TO KETAMINE

open access: yesThe Iraqi Journal of Medical Sciences, 2018
Background: Ketamine is N-methyl-D-aspartate (NMDA) receptors blocking drug, it affects the cerebral cortex and play an essential role in learning and memory.
Mohanad Najm   +2 more
doaj   +1 more source

The neural correlates of regulating another person's emotions: an exploratory fMRI study [PDF]

open access: yes, 2014
Studies investigating the neurophysiological basis of intrapersonal emotion regulation (control of one's own emotional experience) report that the frontal cortex exerts a modulatory effect on limbic structures such as the amygdala and insula. However, no
Eleanor eMiles   +12 more
core   +4 more sources

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

open access: yesAdvanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang   +17 more
wiley   +1 more source

Relationships between human auditory cortical structure and function [PDF]

open access: yes, 2003
The human auditory cortex comprises multiple areas, largely distributed across the supratemporal plane, but the precise number and configuration of auditory areas and their functional significance have not yet been clearly established.
Hall, DA, Hart, HC, Johnsrude, IS
core   +2 more sources

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

open access: yesAdvanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong   +10 more
wiley   +1 more source

Drawing cartoon faces - a functional imaging study of the cognitive neuroscience of drawing [PDF]

open access: yes, 2009
We report a functional imaging study of drawing cartoon faces. Normal, untrained participants were scanned while viewing simple black and white cartoon line-drawings of human faces, retaining them for a short memory interval, and then drawing them ...
Gowen, Emma   +2 more
core   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

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