Results 41 to 50 of about 92,117 (241)

Aging and the Spectral Properties of Brain Hemodynamics

Advanced Science, EarlyView.
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park, Abraham Z. Snyder, Manu S. Goyal, Timothy O. Laumann, John J. Lee, Babatunde Adeyemo, Nicholas Metcalf, Andrei G. Vlassenko, Joshua S. Shimony, Eric C. Leuthardt   +9 more
wiley   +1 more source

Molecular Evolution of a Glioblastoma Controlled With Tumor Treating Fields and Concomitant Temozolomide

Frontiers in Oncology, 2018
Tumor Treating Field (TTFields) therapy has demonstrated efficacy in a Phase 3 study of newly diagnosed glioblastoma (GB) following radiation (RT) and temozolomide (TMZ).
H. Ian Robins, H. Ian Robins, H. Ian Robins, HuyTram N. Nguyen, Aaron Field, Steven Howard, Shahriar Salamat, Dustin A. Deming, Dustin A. Deming   +8 more
doaj   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Clinical case of treatment of a patient with pulmonary embolism after microsurgical excision of arteriovenous malformation of the right parietal lobe

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2022
The article presents a clinical observation of successful treatment of a patient with intrahospital hemodynamically significant pulmonary embolism, which frolicked in the first 35 hours after bone-plastic trepanation in the right temporal-parietal region
A. G. Pronin, N. Y. Sivokhina, M. A. Maslennikov, V. V. Artsishevskay, A. S. Salov, A. R. Rakhmatullina, D. K. Glukhov   +6 more
doaj   +1 more source

Dedifferentiation and Transfer in Executive Function and Math Ability Following a Five‐Year Abacus Training in Schoolchildren

Advanced Science, EarlyView.
While cognitive development typically exhibits differentiation, marked by decreasing inter‐domain correlations, this study demonstrates that five‐year abacus training is associated with de‐differentiation of executive function and mathematical ability in school‐aged children.
Tianyong Xu, Xinyang Liu, Hongjian He, Changsong Zhou, Andrea Hildebrandt, Feiyan Chen   +5 more
wiley   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

Advanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu, Nan Li, Yi‐Wen Lv, Wen‐Miao Yang, Zhi‐Yun Yu, Yi‐Min Zhang, Yu Guo, Xiao‐Yin Chen   +7 more
wiley   +1 more source

Parietal Lobes in Schizophrenia: Do They Matter? [PDF]

Schizophrenia Research and Treatment, 2011
Objective. Despite observations that abnormal parietal lobe (PL) function is associated with psychotic-like experiences, our knowledge about the nature of PL involvement in schizophrenia is modest. The objective of this paper is to investigate the role of the PL in schizophrenia.Method.
Gregor Berger, Murat Yildiz, Stefan Borgwardt   +2 more
openaire   +2 more sources

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study

Frontiers in Neuroscience
IntroductionElectroencephalographic (EEG) abnormalities, such as increased theta power, have been proposed as biomarkers for neurocognitive disorders. Advancements in amyloid positron emission tomography (PET) imaging have enhanced our understanding of ...
Jaesub Park, Jaesub Park, Woo Jung Kim, Woo Jung Kim, Han Wool Jung, Han Wool Jung, Jae-Jin Kim, Jae-Jin Kim, Jin Young Park, Jin Young Park, Jin Young Park   +10 more
doaj   +1 more source

Exploring the Effects of 3D Gaze Stimulation and Color Performance in Augmented Reality‐Based Steady‐State Visual Evoked Potential

Advanced Intelligent Systems, EarlyView.
This study investigates how gaze mode and stimulus brightness affect augmented reality‐based steady‐state visual evoked potentials (AR‐SSVEP) brain‐computer interface (BCI) performance. Experiments with 20 participants show that binocular gaze improves recognition accuracy and stimulus luminance impacts performance.
Yiting Geng, Banghua Yang, Mengao Guo, Yuan Yao, Yonghuai Zhang, Luting Chen, Xinxing Xia   +6 more
wiley   +1 more source