Results 101 to 110 of about 661,408 (292)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration

open access: yesAdvanced Science, EarlyView.
Schematic representation of contrast agent clearance by convective bulk flow from the ventricular spaces to the subarachnoid space on the ventral aspect of the brain, or by diffusion into the parenchyma across the pia‐glia or through the semi‐permeable ependyma. Abstract Fluid and solute exchange between cerebrospinal fluid (CSF) spaces and the central
Yann Decker   +2 more
wiley   +1 more source

Oxygen Vacancy Formation at Metal‒TiO₂ Interface Yielding Enhanced Photocatalytic Hydrogen Generation

open access: yesAdvanced Science, EarlyView.
In this work, the oxygen vacancy formation is reported at the Au‐TiO2 interface in strong metal‐support interaction (SMSI) photocatalyst. The oxygen vacancies faciliate electron transfer and favor the adsorption of water and methanol at photocatalyst surface, thus enhancing the kinetic of photocatalytic hydrogen generation. The SMSI concept is extended
Vien‐Duong Quach   +12 more
wiley   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

Dynamic Bonds Reinforced Polyamide Elastomer for Biomedical Orthosis

open access: yesAdvanced Science, EarlyView.
A dynamic bonds (DBs) reinforced shape memory polyamide elastomer is developed using reactive extrusion. Dynamic covalent networks enhance interlayer adhesion in 4D‐printed objects by utilizing the combined effects of multiple DBs, reducing mechanical anisotropy and improving the mechanical and shape memory properties.
Zhen Li   +12 more
wiley   +1 more source

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