Angewandte Chemie, EarlyView.An exception or the rule? This work represents a second observation, and the first crystallographic evidence, of true intercalation of a small‐molecule ligand (here, bisquinolinium PyDH2) into an antiparallel G‐quadruplex (G4) DNA fold. Abstract G‐quadruplexes (G4s) are non‐canonical DNA structures implicated in a number of biological processes.
Kailey N. Martin +7 more
wiley +2 more sources
Association of epinephrine and outcome in cardiac arrest with refractory shockable rhythm: a population-based, propensity-score matched analysis. [PDF]
Crit CareFanet L +10 more
europepmc +1 more source
Children With 22.Q.11.2 Deletion Syndrome: Sleep‐Disordered Breathing and Management
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Patients with 22q11.2 deletion syndrome (22q11DS) are predisposed to obstructive sleep apnea (OSA) due to an abnormal craniofacial anatomy with pharyngeal hypotonia, retrognathia, micrognathia, and glossoptosis. The aim of the study was to describe the prevalence and management of OSA in a cohort of children with 22q11DS.
Domenico Paolo La Regina +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A metastable cyclodextrin monomer can form kinetically trapped supramolecular polymer at low pH. Raising the pH triggers gradual depolymerization into the self‐included monomer with a rate that can be preset by tuning the pH value. The pH‐dependence is directly associated with the rigidity of the cyclodextrin bridge, which is modulated by protonation ...
Wenting Hu +7 more
wiley +2 more sources
Unhealthy Behaviours and All-Cause Mortality Among People With Chronic Hepatitis B, With and Without Hepatitis Delta (ANRS CO22 HEPATHER). [PDF]
J Viral HepatRamier C +9 more
europepmc +1 more source
Art. XXVII.—Account of a rare, if not unique, manuscript History of the Seljúqs contained in the Schefer Collection lately acquired by the Bibliothèque Nationale in Paris [PDF]
, 1902 Edward Granville Browne
openalex +1 more source
Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis
Asian Journal of Organic Chemistry, EarlyView.This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley +1 more source
Asymmetric Intramolecular α‐Arylation of Polar Amino Acids Bearing β‐Leaving Groups
Angewandte Chemie, EarlyView.Use of enolate chemistry to functionalise amino acids with β‐heteroatom side‐chains (serine, cysteine, threonine, etc.) is hampered by β‐elimination. We show that α‐arylation can be achieved by incorporating the side chain into a saturated heterocycle, making the unwanted elimination a disfavoured 5‐endo‐trig reaction.
Ömer Taspinar +6 more
wiley +2 more sources
An enigmatic abdominal mass presenting 1 year after childbirth. [PDF]
Hepatobiliary Surg NutrCubisino A, Grégory J, Beaufrère A.
europepmc +1 more source