Results 181 to 190 of about 661,408 (292)

Correction: Once-weekly IcoSema versus once-weekly semaglutide in adults with type 2 diabetes: the COMBINE 2 randomised clinical trial. [PDF]

open access: yesDiabetologia
Lingvay I   +9 more
europepmc   +1 more source

Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorder. [PDF]

open access: yesEBioMedicine
Joza S   +40 more
europepmc   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

open access: yesAngewandte Chemie International Edition, Accepted Article.
These studies reveal the first structure of Clostridiumacetobutylicum alcohol dehydrogenase (CaADH), a protein exhibiting remarkable substrate promiscuity and stereochemical fidelity. The CaADH enzyme is utilized here for synthesizing 20 potential aryl isoserine side chains for the Taxotère family of tubulin‐binding chemotherapeutics.
Gaurav P. Kudalkar   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy