Results 201 to 210 of about 4,352,696 (267)

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

Advanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr, Andreas D. Meid, Eric Mühlberg, Manuel Ben Böhmann, Julian Quehenberger, David Wurm, Mikko Gynther, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
wiley   +1 more source

Extended Fused Carbazole‐BODIPY, High Brightness NIR Organic Dyes

Angewandte Chemie, EarlyView.
Highly fused boron‐dipyrromethene (BODIPY) with a strong donor group has been synthesized, and their photophysical behaviors fully characterized. They exhibit outstanding brightness for fluorophores emitting in the NIR region. Water‐soluble nanoparticles filled with one of these dyes demonstrate high efficiency as the NIR II visualization agent ...
Fabien Ceugniet, Valentin Ott, Pascal Retailleau, Yann Bretonniere, Olivier Maury, Manon H. E. Bousquet, Lucie Sancey, Nicolas Leclerc, Denis Jacquemin, Gilles Ulrich   +9 more
wiley   +2 more sources

Utility of continuous EEG monitoring in postanoxic coma: finding the right balance. [PDF]

Crit Care
Ayasse T, Cariou A, Benghanem S.
europepmc   +1 more source

Induced Photoelectron Circular Dichroism as a Probe for Distinguishing Diastereotopic Lone Electron Pairs

Angewandte Chemie, EarlyView.
Gas‐phase complexation of chiral methyloxirane by achiral phenol results in induced chiroptical response of phenol. Two pseudo enantiomer complexes are observed, corresponding to hydrogen bonding from phenol to either of the lone electron pair of the methyloxirane oxygen, denoted as Pro R and Pro S, with opposite chiral deformation of phenol and ...
Etienne Rouquet, Valéria Lepère, Gustavo A. Garcia, Laurent Nahon, Rodolphe Vuilleumier, Anne Zehnacker   +5 more
wiley   +2 more sources

Correction to: Clinical and polysomnographic changes in idiopathic hypersomnia ten years after the diagnosis. [PDF]

J Clin Sleep Med
Leu-Semenescu S, Maranci JB, Dudoignon B, Gales A, Sallansonnet-Froment M, Dodet P, Arnulf I.   +6 more
europepmc   +1 more source

Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation

Angewandte Chemie, EarlyView.
The total synthesis of the bis‐indole alkaloid (−)‐owerreine has been accomplished by a diastereoselective [4+2] annulation between an enamine and an α,β−unsaturated indolenine precursor to form the 3‐spirocyclic tetrahydropyridine linkage of the natural product. DFT calculations allow an understanding of the mechanism of the key annulation.
Elisa Coll, Vincent Gandon, Cyrille Kouklovsky, Laurent Evanno, Guillaume Vincent   +4 more
wiley   +2 more sources

Expert consensus-based clinical practice guidelines for Care and weaning procedures in tracheostomized ICU patients after invasive mechanical ventilation: a joint statement by the Intensive Care Physiotherapy Society (SKR) and the French Intensive Care Society (SRLF). [PDF]

Ann Intensive Care
Medrinal C, Delemazure J, Billard M, Carpentier D, Choukroun G, Combret Y, De Crouy AC, López CD, Dugernier J, Farcy M, Foudhaili A, Gallice T, Gatignol P, Ghelab Z, Houze MH, Jezequel M, Latier AC, Marzouk M, Morawiec E, Piquilloud L, Ruttimann A, Sanchez P, Terzi N, Thille AW, Reffienna M.   +24 more
europepmc   +1 more source

PFR PARIS 2023

European Journal of Volunteering and Community-Based Projects
Kim Charles Nguyen, Clément Rateau Boissé, Eloïse Marie Clotilde Pourchet   +2 more
doaj  

CMV seropositivity associates with poor clinical outcome in triple negative breast cancer. [PDF]

iScience
Seban RD, Lamy C, Cabel L, Roux H, Da Silva ID, Djerroudi L, Gorret D, Lalanne AI, Louis D, Milder M, Reyal F, Laas E, Bonneau C, Pouget N, Sablin MP, Pierga JY, Dupain C, Berger F, Buvat I, Bidard FC, Vincent-Salomon A, Le Tourneau C, Alanio C, Lantz O.   +23 more
europepmc   +1 more source

One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade

Angewandte Chemie, EarlyView.
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra, Ruzal Sitdikov, Hasil Aman, Alyssio Calis, Gergely Laczkó, Virgile Rouffeteau, Maxime R. Vitale, Imre Pápai, Oscar Verho   +8 more
wiley   +2 more sources