Results 151 to 160 of about 150,869 (293)

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Diagnosing OSA and Insomnia at Home Based Only on an Actigraphy Total Sleep Time and RIP Belts an Algorithm “Nox Body Sleep™”

Nature and Science of Sleep
Damien Leger,1,2 Maxime Elbaz1,2 1Université Paris Cité, (VIFASOM), ERC 7330 VIgilance FAtigue SOMmeil, Paris, France; 2Assistance Publique-Hôpitaux de Paris (APHP) Hôtel Dieu, Centre du Sommeil et de la Vigilance, Paris, FranceCorrespondence: Damien ...
Leger D, Elbaz M
doaj  

Credibility dilemmas under the Paris agreement: explaining fossil fuel subsidy reform references in INDCs. [PDF]

Int Environ Agreem, 2022
Elliott C, Bernstein S, Hoffmann M.
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

The Negotiating History of the Paris Agreement [PDF]

, 2017
The most important climate agreement in history, the Paris Agreement on Climate Change represents the commitment of the nations of the world to address and curb climate change.Signed in December 2015, it entered into force on 4th November 2016. Countries
Doelle, Meinhard, Klein, Daniel, Bulmer, Jane   +2 more
core  

The public health implications of the Paris Agreement: a modelling study. [PDF]

Lancet Planet Health, 2021
Hamilton I, Kennard H, McGushin A, Höglund-Isaksson L, Kiesewetter G, Lott M, Milner J, Purohit P, Rafaj P, Sharma R, Springmann M, Woodcock J, Watts N.   +12 more
europepmc   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Achieving the ambitious targets of the Paris Agreement: the role of key actors. [PDF]

Int Environ Agreem, 2021
Andresen S, Bang G, Skjærseth JB, Underdal A.   +3 more
europepmc   +1 more source

Hydrogel Stack‐Tailored Logics and High‐Fidelity Multimodal Sensors Promoted by Precisely Evaluated Ionic Migration

Advanced Science, EarlyView.
Inspired by biological ion transport, this work introduces self‐powered multifunctional sensors utilizing tailored hydrogel stacks. Optimizing ionic migration with MXenes and carbon nanotubes achieves high‐performance energy harvesting and unique logic circuit functionality.
Haoran Chen, Hongjian Zhang, Zhonghui Shen, Taeuk Eom, Hyunseung Kim, Delong He, Jinbo Bai, Geon‐Tae Hwang, Yong Zhang, Chang Kyu Jeong   +9 more
wiley   +1 more source