Results 41 to 50 of about 940,572 (293)

Pledging, Populism, and the Paris Agreement: The Paradox of a Management-Based Approach to Global Governance [PDF]

, 2019
For many observers, the Paris Agreement signaled a historic breakthrough in addressing the problem of global warming. In its basic design, however, the Agreement is far from novel.
Coglianese, Cary
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Impact of U.S. Re‐engagement in Climate on the Paris Targets

Earth's Future, 2021
The Paris Agreement seeks to combine international efforts to keep global temperature increase to well‐below 2°C. Whilst current ambitions in many signatories are insufficient to achieve this goal, optimism prevailed in the second half of 2020.
Dirk‐Jan van de Ven, Michael Westphal, Mikel González‐Eguino, Ajay Gambhir, Glen Peters, Ida Sognnaes, Haewon McJeon, Nathan Hultman, Kevin Kennedy, Tom Cyrs, Leon Clarke   +10 more
doaj   +1 more source

Non-state actors in hybrid global climate governance: justice, legitimacy, and effectiveness in a post-Paris era [PDF]

, 2017
In this article, we outline the multifaceted roles played by non-state actors within the United Nations Framework Convention on Climate Change and place this within the wider landscape of global climate governance.
Kuyper, Jonathan W., Linnér, Björn‐Ola, Schroeder, Heike   +2 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

$$K^0_S$$ K S 0 meson production in inelastic p+p interactions at 31, 40 and 80  $$\text {Ge}\hspace{-1.00006pt}\text {V}\!/\!c$$ Ge V / c beam momentum measured by NA61 $$/$$ / SHINE at the CERN SPS

European Physical Journal C: Particles and Fields
The yields of $$K^0_S$$ K S 0 mesons have been measured in inelastic p+p interactions at incident projectile momenta of 31, 40 and 80  $$\text {Ge}\hspace{-1.00006pt}\text {V}\!/\!c$$ Ge V / c ( $$\sqrt{s_{NN}}=7.7, 8.8$$ s NN = 7.7 , 8.8 and 12.3 ...
NA61/SHINE Collaboration, N. Abgrall, H. Adhikary, P. Adrich, K. K. Allison, N. Amin, E. V. Andronov, T. Antićić, I.-C. Arsene, M. Bajda, Y. Balkova, M. Baszczyk, D. Battaglia, A. Bazgir, S. Bhosale, M. Bielewicz, A. Blondel, M. Bogomilov, Y. Bondar, N. Bostan, A. Brandin, A. Bravar, W. Bryliński, J. Brzychczyk, M. Buryakov, A. F. Camino, M. Ćirković, M. Csanád, J. Cybowska, T. Czopowicz, C. Dalmazzone, N. Davis, A. Dmitriev, P. von Doetinchem, W. Dominik, P. Dorosz, J. Dumarchez, R. Engel, G. A. Feofilov, L. Fields, Z. Fodor, M. Friend, M. Gaździcki, O. Golosov, V. Golovatyuk, M. Golubeva, K. Grebieszkow, F. Guber, A. Haesler, S. N. Igolkin, S. Ilieva, A. Ivashkin, A. Izvestnyy, K. Kadija, N. Kargin, N. Karpushkin, E. Kashirin, M. Kiełbowicz, V. A. Kireyeu, H. Kitagawa, R. Kolesnikov, D. Kolev, A. Korzenev, Y. Koshio, V. N. Kovalenko, S. Kowalski, B. Kozłowski, A. Krasnoperov, W. Kucewicz, M. Kuchowicz, M. Kuich, A. Kurepin, A. László, M. Lewicki, G. Lykasov, V. V. Lyubushkin, M. Maćkowiak-Pawłowska, Z. Majka, A. Makhnev, B. Maksiak, A. I. Malakhov, A. Marcinek, A. D. Marino, H.-J. Mathes, T. Matulewicz, V. Matveev, G. L. Melkumov, A. Merzlaya, Ł. Mik, A. Morawiec, S. Morozov, Y. Nagai, T. Nakadaira, M. Naskręt, S. Nishimori, V. Ozvenchuk, O. Panova, V. Paolone, O. Petukhov, I. Pidhurskyi, R. Płaneta, P. Podlaski, B. A. Popov, B. Pórfy, M. Posiadała-Zezula, D. S. Prokhorova, D. Pszczel, S. Puławski, J. Puzović, R. Renfordt, L. Ren, V. Z. Reyna Ortiz, D. Röhrich, E. Rondio, M. Roth, Ł. Rozpłochowski, B. T. Rumberger, M. Rumyantsev, A. Rustamov, M. Rybczynski, A. Rybicki, K. Sakashita, K. Schmidt, A. Yu. Seryakov, P. Seyboth, U. A. Shah, Y. Shiraishi, A. Shukla, M. Słodkowski, P. Staszel, G. Stefanek, J. Stepaniak, M. Strikhanov, H. Ströbele, T. Šuša, L. Swiderski, J. Szewiński, R. Szukiewicz, A. Taranenko, A. Tefelska, D. Tefelski, V. Tereshchenko, A. Toia, R. Tsenov, L. Turko, T. S. Tveter, M. Unger, M. Urbaniak, F. F. Valiev, D. Veberič, V. V. Vechernin, V. Volkov, A. Wickremasinghe, K. Wójcik, O. Wyszyński, A. Zaitsev, E. D. Zimmerman, A. Zviagina, R. Zwaska   +158 more
doaj   +1 more source

The Paris Agreement: Short-Term and Long-Term Effectiveness

Politics and Governance, 2016
The 2015 Paris Agreement was widely greeted with enthusiasm. We assess the short-term and long-term potential effectiveness of Paris. Concerning short-term effectiveness, we contend that while Paris scores high on participation, and reasonably high on ...
Guri Bang, Jon Hovi, Tora Skodvin
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

How can Azerbaijan meet its Paris Agreement commitments: assessing the effectiveness of climate change-related energy policy options using LEAP modeling

Heliyon, 2020
Azerbaijan has committed to cut GHG emissions by 35% by 2030 under the Paris Agreement. By applying LEAP, a well-regarded forecasting model based on inventories defined under the IPCC (Intergovernmental Panel on Climate Change), GHG emissions projections
Troy B. Felver
doaj   +1 more source

The impact of the Paris Agreement on the change in the framework for climate and energy policy of the European Union and its legal regulations [PDF]

, 2017
Porozumienie paryskie do Ramowej Konwencji Narodów Zjednoczonych w sprawie zmian klimatu stało się bezpośrednim bodźcem do przyjęcia Ramowej polityki klimatyczno-energetycznej do roku 2030, w której sformułowano wkład UE i państw członkowskich w ...
Sobieraj, Kamila
core   +2 more sources