Results 101 to 110 of about 3,081,065 (308)

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Dilute but Dense – Reversible Crosslinking Enables Water‐Rich (Bio)polymer Condensates

Advanced Science, EarlyView.
Reversible crosslinking between two types of (bio)polymers drives liquid–liquid phase separation even in good solvent. The arrangement of binding motifs controls condensate formation and density, and internal network structure. Simulations and theory reveal a closed‐loop coexistence phase diagram at very low monomer concentrations and re‐entrant ...
Xinxiang Chen, Jude Ann Vishnu, Pol Besenius, Julian König, Friederike Schmid   +4 more
wiley   +1 more source

The Bumpy Road from Paris to Brussels: The European Commission Governance Incentive Tranche [PDF]

The EC recently launched a new aid instrument for the ACP-community: the “governance incentive tranche”, a modality designed to incentivise ACP-governments to carry out governance reforms. In this paper we analyse whether this new initiative incorporates
Molenaers, Nadia, Nijs, Leen
core   +1 more source

Gravity‐Tolerant In‐Flight 3D Bioprinting Enabled by Stereolithography for Space Tissue Engineering

Advanced Science, EarlyView.
A flight‐compliant, closed stereolithographic 3D bioprinting system enables robust fabrication of acellular and cell‐laden hydrogel constructs under varying gravitational conditions, including microgravity and hypergravity phases. Printed structures retain dimensional fidelity and high‐resolution features, while cell viability remains high ...
Bianca Lemke, Matthias R. Kollert, Tobias Lam, Tobias Thiele, Nicolas Göbel, Lisa R. Köhn, Gabriela Korus, Lutz Kloke, Georg N. Duda   +8 more
wiley   +1 more source

The Paris Principles, NHRIs, and Enabling Legal Frameworks

, 2021
This article examines four national enforcement models with respect to employment discrimination claims against the requirement of enabling legal frameworks for National Human Rights Institutions (“NHRIs”) set out under the Paris Principles. The four models identified are the private enforcement as typified by the United Kingdom, hybrid agency-private ...
openaire   +1 more source

Is Sustainability Attractive for Corporate Real Estate Decisions ? [PDF]

This paper provides an analysis of the impact of sustainable principles on corporate property decisions and attractiveness for business districts in the French context.
Aurélien Décamps, Ingrid Nappi-Choulet
core  

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Jak ESG pravidla a udržitelnost formují veřejné finance a daně?

Acta Universitatis Carolinae. Iuridica
In recent years, ESG criteria and sustainability principles have expanded beyond the private sector to increasingly influence public finance legislation.
Radim Boháč, Petra Kerndlová
doaj   +1 more source

The paradigm compiler: Mapping a functional language for the connection machine [PDF]

The Paradigm Compiler implements a new approach to compiling programs written in high level languages for execution on highly parallel computers. The general approach is to identify the principal data structures constructed by the program and to map ...
Dennis, Jack B.
core   +1 more source

Transnational Perspectives on the Paris Climate Agreement Beyond Paris: Redressing American Defaults in Caring for Earth’s Biosphere [PDF]

, 2019
Anxiety about the fate of human civilization is rising. International Law has an essential role to play in sustaining community of nations. Without enhancing International Environmental Law, the biosphere that sustains all nations is imperiled.
Robinson, Nicholas A.
core   +2 more sources